Advanced Biophysical/Physical Modeller

Do you have a passion for Science? Are you experienced in biophysical and/or physical modelling and enthusiastic, motivated and willing to learn? Then AstraZeneca might be the one for you!

At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person.

We have an exciting opportunity for an Advanced Biophysical/Physical Modeller to join our team! This position is within Pharmaceutical Technology and Development and will be based at our site in Gothenburg, Sweden, or at our site in Macclesfield, UK.

Pharmaceutical Technology and Development (PT&D) is the organisation that turns brilliant science into actual medicines that help millions of people. We work across the entire value chain, designing and delivering active ingredients, formulations and devices for new medicines and providing expert technical support to all AZ's commercial drug substances and products to ensure we successfully supply medicines to patients. In Product Development, a department in Pharmaceutical Technology and Development, we focus on the design and development of commercial products and processes, contribute to new product introductions and to the continuous improvement of launched products. Product Development have recently created the Modelling & Simulation team, a strategic global team of experts covering a wide range of Modelling & Simulation expertise, with members based in Gothenburg and in Macclesfield.

What you'll do
In this role you will work collaboratively with a variety of scientific specialists and project managers across a global organization to effectively deliver advanced modelling solutions and play a key role in shaping and driving the Modelling & Simulation strategy.
The role holder will typically:

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Translate complex biophysical, physical, biopharmaceutical, pharmaceutical problems into appropriate mechanistic/first principles models and deliver timely solutions.
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Work collaboratively with experimentalists with different backgrounds to identify Modelling & Simulation opportunities and to strategically direct experimentation.
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Drive and champion the organizational digital transformation.
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Establish strong working relationships with the Modelling & Simulation team members and with other colleagues in Product Development to enable an impact-driven application of Modelling & Simulation.
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Develop, validate and implement Modelling & Simulation protocols to be used by the wider scientific community in Product Development.

Essential for the role

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MSc/PhD in physical chemistry, biophysics, physics, engineering, mathematics, computational biology or another relevant area.
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Strong expertise in relevant programming and scripting languages, e.g. Matlab, C++, Python or similar, and willingness to learn.
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Academic and/or industrial experience in the development and implementation of first principle/mechanistic models describing, e.g., biophysics, computational biology, biopharmaceutics, physical chemistry, or transport phenomena.
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Strong motivation to understand pharmaceutical/biopharmaceutical development activities to design, manufacture and evaluate drug products.
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Ability to provide scientific leadership, coaching and mentorship for less experienced Modelling & Simulation scientists and for the wider Product Development community.
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Strong collaboration, communication, influencing and networking skills.


Desirable for the role

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Experience in the application of first principle/mechanistic models in the design and performance evaluation of pharmaceutical/biopharmaceutical products and processes.
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Working experience in the pharmaceutical/biopharmaceutical/food/cosmetics and personal care/fast-moving consumer goods industry.
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Knowledge/strong interest in in-vivo performance of pharmaceutical/biopharmaceutical products.
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Track record of scientific publications in the Modelling & Simulation area.


What's next!
Are you an expert in this area looking for an opportunity to apply your expertise in a company that turns brilliant ideas into life changing medicines? Apply now!
We would like to know more about you. Welcome with your application, including CV and cover letter, no later than March 17, 2021.


Where can I find out more?
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