Analytical Scientist - Advanced Drug Delivery

At AstraZeneca, we turn ideas into life changing medicines and strive to continuously meet the unmet needs of patients worldwide. Working here means being entrepreneurial, thinking big, and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person.

Pharmaceutical Sciences is a department within AstraZeneca Biopharmaceutical R&D. The Pharmaceutical Sciences' mission is to transform molecules into investigational medicines, meeting the unmet needs of future patients. Advanced Drug Delivery (ADD) is a department in Pharmaceutical Sciences. Our portfolio of projects spans traditional small molecules, peptides oligonucleotides to RNA based therapeutics across AstraZeneca's therapy areas and our mission is to transform diverse modalities into investigational medicines.

We now seek a dedicated and motivated analytical scientist to join our Preformulation team in Gothenburg, Sweden. The remit of the team is to deliver small molecule support to projects up to CDID, where one compound is chosen to go further to clinical development.

What you'll do

This is an exciting role where you as an analytical scientist are anticipated to perform and evaluate theoretical and experimental stability assessments looking for potential degradation pathways. You will develop new stability indicating methods for our pre-clinical formulations, and set up methods for the validation of the quality of our products. The work is done in multiple projects in parallel, and the work is performed as part of different multi-skilled drug development project teams. You will also participate in scientific initiatives and technical improvement development within the department to increase the scientific knowledge and simplify our data generation and handling. You will work in close collaboration with formulation scientists, analytical chemists, solid state scientists as well as biopharmaceutics experts in Gothenburg, Sweden, but also with colleagues in UK and US. Profound knowledge of the discovery and development phase as well as awareness of clinical drug development are central for being successful in this role.

Essential requirements

* Master's degree (CLC) in a relevant subject area (e.g. Analytical Chemistry, Biochemistry or Biotechnology) or equivalent industrial experience within pharmaceutical drug development
* Proven experience of analytical methodologies for small synthetic molecules, with focus on the liquid chromatography aspects.
* Experience in planning and performing forced degradation studies and GLS stability investigations for pre-clinical GLP studies for small synthetic molecules.
* Extensive experience with HPLC method development for small synthetic molecules.
* Experience in using automated systems for compound stability studies.
* Experience in using both UV and MS detection for determination of compound and product stability.
* Experience of presenting scientific findings in writing and presentations with ability to communicate and write proficiently in English.
* Extensive practical laboratory experience of liquid chromatography methods.



Additional capabilities desirable for the role

* Good communication skills, and the ability to discuss complex ideas in a simple, easy to understand way
* Ability to tackle complex scientific problems and troubleshooting, and independently lead project related work from an analytical perspective
* Profound knowledge of the discovery and development phase and awareness of clinical drug development.

If your passion is science and you want to be part of a team that makes a big impact on patients' lives, then there's no better place to be. With us there are many opportunities to develop yourself and your career. From our diverse portfolio and teamwork, to our cutting-edge innovations - it's a place for lifelong learning.

So, what's next? Interviews will be held ongoing. Apply now!