Associate Director - Immunoassay Specialist

Join our dedicated team at AstraZeneca as an Associate Director - Immunoassay Specialist in the Integrated Bioanalysis (iBA) Global Team, based in our research hub Gothenburg. Our iBA group provides broad discovery, preclinical, and clinical support across all therapeutic areas. As part of the Discovery Bioanalysis Group within iBA, you will take a lead role in the lab, designing bioanalysis method strategies and interpreting data generated in support of the broad array of therapeutic modalities within the AstraZeneca drug pipeline.



What you will do

You will strengthen the Discovery Bioanalysis team with your technical & laboratory expertise in ligand binding-immunoassays for the support of pharmacokinetics and biomarker activities to better understand drug actions and their association with pharmacodynamics. You will need to use your experience and consistent track record to design, develop and deliver robust bioanalytical strategies and associated bioanalytical methods; you will need to ensure that assays are shown to be fit-for-intended purpose and provide data that will allow project teams to make informed decisions with confidence. As a Subject Matter Expert, you will be responsible for enhancing the iBA reputation for scientific excellence by presenting at internal and external meetings, and publishing manuscripts. You will be expected to represent the department on multidiscipline, cross functional, drug development teams and work alongside colleagues & stakeholders across iBA and CPSS functions and partner organisations.



Essential Experience & Skills

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A PhD level scientist with a strong background in a biological or chemical related discipline with extensive experience of developing immunoassay methods for the quantitative measurement of biotherapeutics such as nucleotides and proteins.
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A bioanalytical subject matter expert with a broad array of technical and scientific experience to develop, optimise, qualify & troubleshoot ligand binding-immunoassay methods (including ELISA, Gyrolab, and MSD).
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Innovative and influential bioanalytical leader capable of defining, leading and implementing robust bioanalytical strategies, risk mitigations and solutions to challenges in support of diverse project teams.
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A high level of independence with an ability to think & act creatively to develop hypotheses and execute analysis plans for generation and interpretation of pharmacokinetics, pharmacodynamics and biomarker data.
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Proven experience of successfully deploying immunoassays for the assessment of pharmacokinetic, pharmacodynamic and biomarker endpoints in a range of matrices including blood and tissues.
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Proven experience as a scientific expert across a range of therapeutic modalities and able to discern the advantages and pitfalls of a range of analytical techniques.
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In depth knowledge of bioA/biomarker concepts such of "context of use or fit for purpose assay validation/qualification".
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Scientific leader with proven ability to coach and mentor colleagues and junior staff.



To be successful in this role, you need to have effective communication and collaboration skills. Having diligent record-keeping skills and the ability to interpret integrated datasets are critical for success. Furthermore, you need to have the ability to oversee multiple projects and/or tasks concurrently in a fast-paced environment. We expect you to have a proven track record of publication & presentations in the large molecule and bioanalysis field.



Desirable Experience

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Applied knowledge of bioanalytical techniques that would strengthen the departments bioA toolbox e.g., Flow Cytometry, HPLC-MS/MS, high sensitivity immunoassay platforms, qRT-PCR, dd-PCR.
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Experience with a broad array of multiomics techniques including, but not limited to, proteomics, metabolomics, lipidomic, RNAseq, cell- painting or genomics applications.
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Contributed to regulatory submission documentation such as INDs, CTAs, IBs, ISI and/or NDAs/BLAs and experience in regulatory authority responses across multiple geographies.
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Proven experience of operational streamlining and use of innovation tools, such as AI, within the workplace.





Why AstraZeneca?

At AstraZeneca, we follow the science to explore and innovate. We are working towards treating, preventing, modifying and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference. We have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. It's our combination of curiosity and courage that drives us, inspired by the possibility of doing things that have never been done before.



Are you ready to make a meaningful impact on patients' lives?Does this sound like your next challenge and a good workplace for you?



Welcome with your application no later than April 26, 2024.