Associate Principal Scientist - Medicinal Chemistry

Are you an experienced Scientist ready to apply your skills in a diverse and dynamic company? If your passion is science and you want to be part of a team that makes a bigger impact on patients' lives, then there's no better place to be.

We are looking to hire a Senior Research Scientist (SRS) or an Associate Principal Scientist (APS) within our Medicinal Chemistry department in the area of Respiratory & Immunology. You will get the opportunity to join a highly creative and collaborative discovery team embedded in a science driven environment, leveraging innovative Organic and Medicinal Chemistry to invent novel drug candidates. Depending on the qualification and previous professional experience of the selected candidate, we are considering a Senior Research Scientist or an Associate Principal scientist for this position.

We are searching for a small molecule Medicinal chemist who will be working within a department driving discovery research across small molecules, Proteolysis Targeting Chimeras (PROTACs), peptides and oligonucleotides. Our department embraces the diversity of talents and allows the teams to grow and learn together to accomplish our collective goal to improve the quality of life for patients.

What you'll do

As an SRS/APS in the Early R&I Medicinal Chemistry department you will play an important role in advancing drug discovery projects from target validation to preclinical phase. You will join a highly integrated discovery team leveraging innovative medicinal chemistry to invent novel medicines. Your focus will be on design, synthesis and characterization of drug molecules and you will be expected to lead by example with integrity, to follow the science and collaborate across boundaries. You will ensure uptake of novel scientific developments into project teams and lead compound design by generating creative and novel ideas for our molecules. You will also be expected to share scientific findings to a broader internal and external audience and to publish your results.

We are looking for a person with a strong scientific curiosity and a solid background in Organic Chemistry. Depending on previous professional experience in Medicinal Chemistry, you may qualify as Senior Research scientist or Associate Principal scientist. You should be up-to-date with recent trends in Synthetic Chemistry and have a constant drive to develop skills in Medicinal Chemistry. We are looking forward to a candidate with excellent communication and leadership skills and a strong ability to collaborate across disciplines.



Main Duties and Responsibilities

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Support Early R&I drug discovery programs through design and synthesis of potential drug molecules
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Provide state-of-the-art synthetic organic chemistry to projects at all stages of drug discovery delivering high quality drug molecules and tool compounds
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Collect, analyze and interpret project data. Propose hypotheses and plan how to test them
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Collaborate with the chemistry team in the development, planning and prioritization of route design, sharing findings and jointly solving scientific questions in the projects
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Drive R&I´s scientific reputation by presenting and publishing your results within the department, across AZ and externally
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As APS, you will lead chemistry programs and represent the medicinal chemistry discipline in cross functional teams
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Follow safety requirements and all AZ corporate responsibility policies



Essential for the role

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PhD in synthetic Organic Chemistry, Medicinal Chemistry or Biochemistry
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In-depth scientific knowledge and recent practical experience in the area of synthetic chemistry
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Up-to-date with the application of modern purification and analytical techniques
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A proven track record of delivery from own experimental work
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Excellent communication and collaboration skills
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Knowledge of the pharmaceutical drug discovery and development process
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Professional experience in the Pharmaceutical Industry is required to qualify for the APS level

If you are interested, apply now!

We welcome your application no later than May 20th, 2021.



Why AstraZeneca?



At AstraZeneca we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There's no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development



Where can I find out more?

* Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/
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