Associate researcher

The University of Gothenburg tackles society’s challenges with diverse knowledge. 56 000 students and 6 600 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell – what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them. The Institute is composed of the following four departments:


• The Department of Infectious Diseases
• The Department of Microbiology and Immunology
• The Department of Medical Biochemistry and Cell Biology
• The Department of Laboratory Medicine

At present, the institute has about 360 employees and approximately 450 million SEK in total assets.

The Camuñas-Soler lab stands at the interface of genomics, biophysics, and precision medicine. Our mission is to develop new single-cell technologies and non-invasive molecular diagnostic tools to understand and predict cellular dysfunction in human disease.  Our research is highly interdisciplinary in nature and combines approaches from molecular engineering, biophysics, and computational biology.

As a member of the lab, you will be part of an international and dynamic group of experimental and computational biologists within the Wallenberg Center of Molecular and Translational Medicine (WCMTM) and the Institute of Biomedicine at the University of Gothenburg. The lab is located on the Medicinareberget campus, providing close collaboration with clinical partners in Sahlgrenska University Hospital, the largest hospital in Sweden and second largest in Europe. This creates a unique environment to develop new quantitative tools to study human tissue.  For more information about the lab and team, visit:

https://www.gu.se/en/research/joan-camunas-soler-group

This project seeks to integrate measurements of cell morphology with single-cell transcriptomics. The associate researcher scholar will develop methods to integrate multimodal single-cell sequencing and imaging analysis both from an experimental and data analysis perspective.

Duties 
The main task will be implementing a single-cell pipeline to perform imaging of cells in isolation followed by single-cell RNA sequencing. This will be done using a CellCelector system and other custom-made cherry-picking systems. Methods to perform single-cell sequencing such as SmartSeq2 and 10X genomics will be adapted and implemented in the lab. These tasks will be combined with the generation and analysis of spatial transcriptomics data. Finally, the candidate will perform data analysis and integration among all the generated categories of data. Therefore it is important to have experience analyzing multimodal single-cell data and in particular imaging data combined with sequencing data.

Qualifications 
-MsC in a relevant area such as Biology, Pharmacy, Bioinformatics.

-Experience with single-cell transcriptomic experiments of human samples.

-Experience in combining cellular morphology experiments with single-cell sequencing.

-Knowledge of image analysis techniques such as hyperspectral imaging.

-Knowledge to operate a CellCelector system is a plus.

-Knowledge of single-cell analysis involving cell-to-cell communication.

-Programming techniques: python.

Employment 
The employment is limited (temporary) for 11 months and full-time with placement at the Institute of Biomedicine. First day of employment as agreed.

Contact information for the post 
If you have any questions about the position, please contact Associate Senior Lecturer Joan Camuñas. E-mail: joan.camunas@gu.se

Unions 
Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

 

Application 
To apply for a position at the University of Gothenburg, you have to create an account in our recruitment system. Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline. 

Applications must be received by: 2023-03-29.

The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.