Chemistry Automation Application Specialist

Are you a trained Organic Chemist/Synthesis Chemist with practical experience of using lab automation technologies for setting up and running experiments and synthesizing new molecules? Are you interested in becoming part of a growing team focusing on the autonomous synthesis of bioactive molecules at a company where we are committed to lifelong learning, growth, and development? Welcome to AstraZeneca!

We are seeking an Organic Chemist with extensive experience in applying laboratory automation technologies to the synthesis of new molecules to play an important part in our iLAB team, focusing on building an industry-leading end-to-end chemistry automation platform. You will work as a Chemistry Automation Application Specialist and in this multidisciplinary, multinational team you can drive and advance our chemistry automation capabilities at AstraZeneca in Gothenburg, Sweden.

We are a global, science-led BioPharmaceutical business and our innovative medicines are used by millions of patients worldwide. With our ground-breaking pipeline comes a bright future - a secure job, exciting opportunities, and varied work. You will be valued. Not only for your unique contribution, skills, and background, but because we recognize people are our greatest asset.

What you will do:
In this exciting role you will be responsible for the transfer of manually executed compound synthesis to automation platforms. You will actively develop synthesis protocols for state-of-the-art chemistry transformations to be executed in a fully automated way. As well as intimately be involved in the build of a new end-to-end chemistry automation platform and work with colleagues on the design and implementation of novel automation workflows. You'll identify, test and evaluate new devices and play an important role during factory and site acceptance test activities for the new platform and drive the use of these capabilities in AstraZeneca drug discovery projects.

During your work you will spend approximately 50% of your time in the laboratory investigating how manual syntheses must be modified to be robustly executed in an automated way. You will transfer this knowledge to your colleagues in order to facilitate the automation of synthesis tasks requested by medicinal chemists from across the organization. During the other 50% of your time, you will work together with colleagues on the detailed specification for the future chemistry automation platform and function as an expert user of specific lab automation devices. As our new Chemistry Automation Application Specialist you will have access to the best internal and external science and be expected to enhance business reputation both internally and externally through peer-reviewed publications and oral/poster presentations

Essential in the role:
You're a chemist with a track record of applying innovative chemistry and/or technology solutions, which result in impact on projects. You also have:

* Ph.D. in organic chemistry or a master's degree in chemistry with a minimum of five years industrial experience in synthetic organic chemistry
* Hands on experience with creating custom lab automation workflows and a strong interest in developing new technologies for organic synthesis
* Expertise in theoretical and practical organic synthesis, retrosynthesis, compound route design, purification and analytical chemistry
* Excellent knowledge of current chemical literature, chemical technologies and innovations for driving project delivery

Our new colleague should be motivated to work effectively in hardworking teams and demonstrate ability to work across scientific disciplines to drive project success. We also believe you have the ability to effectively communicate, have a high scientific drive and a long-term commitment to advancing chemistry automation as an innovative tool in drug discovery.

Desirable in the role:

* Experience in planning and executing chemistry experiments in parallel and adapting existing protocols to new applications (e.g., high throughput experimentation, batch-to-flow chemistry, or process scale-up).
* Experience of working in the pharmaceutical/agrochemistry/biotech industry in a discovery environment, including chemistry scale-up labs.
* Experienced with troubleshooting and basic maintenance of instruments (e.g liquid handlers, analytical equipment, flow chemistry reactors).
* Basic programming skills in e.g C#, Python.

Why AstraZeneca?
Join the team unlocking the power of what science can do. We are working towards treating, preventing, modifying, and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world.

So, what's next? If this sounds like your next challenge - apply today! Welcome with your application but send it to us no later than November 13th, 2022.

For more information about the position please contact Dr Michael Kossenjans, Director Chemistry and Head of AZ Chemistry Automation.

Additional information:
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html