Computational Chemist - Oligonucleotide Therapeutics

Are you a skilled Computational Chemist with fruitful experience of computer-aided drug design? Do you want to contribute to the development of an emerging novel category of therapeutics? Great, AstraZeneca might have the position for you!

We are looking for a new colleague to join our Molecular Design team to play an important part as a Computational Chemist - Oligonucleotide Therapeutics. The role is located at our vibrant AstraZeneca R&D site in Gothenburg, Sweden. We will make sure that your scientific experience combined with your high ambition and passion gives you a superb opportunity to influence AstraZeneca's future in applying your skills to drug discovery projects.

Thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment.

What you will do:
In this position, you will have a profound impact on multiple projects across AstraZeneca with a focus applying Computational Chemistry models to discover new drugs. This will involve:

* Apply a variety of computer-aided drug design approaches to support drug development projects.
* Work closely with synthetic chemists with primary focus on the in house proprietary Oligonucleotide Therapeutics Platform and support them with providing modelling and in silico predictions.
* Possibility to develop novel methodologies for addressing the needs of an emerging category of novel therapeutics.
* Plan, write and publish high quality scientific papers.
* Actively participate in mentoring the cohort of Postdocs, PhD students and Master Thesis students in the team.

Essential in the role:
We believe that you have a true passion for computational chemistry and drug design and a degree in chemistry, computer science or another similar field - complemented by experience from molecule design in drug development projects. Your collaboration skills will be of essential importance and you should also have;

* PhD in computational chemistry or relevant industrial experience.
* Experience in drug discovery and/or early development or in a leading academic institution.
* In-depth scientific knowledge in computational chemistry - shown by track record of project deliveries, publications and external presentations.
* Experience with Molecular Dynamics simulations.
* Basic coding skills (shell, Python).

Desirable in the role:

* Good understanding of force field parameterization.
* General understanding of machine learning techniques used for predictive modelling.
* Knowledge in the area of oligonucleotide therapeutics.
* Genuine interest in driving science forward through supervising Master thesis and PhD students

Why AstraZeneca?
At AstraZeneca we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There's no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.

What's next? If this sounds like the place and role for you - apply today!

We look forward to get to know you better! Welcome with your application no later than 15th August, 2021.

For more information about the role please contact hiring manager Atanas Patronov at +46 31 776 3509.

Additional information:
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html

NOTE - Due to summer vacation our communication may be a bit delayed, but will get back with an update on your application later on in August. Thanks in advance for your patience and understanding.