Director of Chemistry - DNA-Encoded & Compound Libraries

Are you an enthusiastic scientific leader with experience in the field of DNA-encoded library chemistry and the enhancement of compound collections, looking to develop yourself and a great team of scientists? At AstraZeneca, we turn ideas into life changing medicines. Working here means thinking big and working together to deliver impact from our contributions that make the impossible a reality.

We have an exciting opportunity in our Discovery Sciences (DS) unit for a Director of Chemistry. This leadership role, in the Compound Synthesis and Management group, provides DNA-encoded library chemistry expertise to the global AstraZeneca portfolio of small molecule Hit-to-Lead projects. In addition, the role provides leadership for the continuous development of the AstraZeneca small molecule compound collection. The position will be placed at our vibrant AstraZeneca R&D site in Gothenburg, Sweden.

As our new Director of Chemistry, you will lead a team of chemists who are passionate about the design and synthesis of DNA-encoded and compound collection libraries, deploying internal synthetic chemistry expertise to develop novel library and off-DNA chemistry, and working with external partners on library production.

We value our differences because we recognise that a team is at its most creative when it is made up of people who think differently from one another, in an environment where different views and perspectives are welcomed and valued. This is how we foster continuous innovation, constant learning and growth for us as individuals and for our patients.

What you'll do:
Lead and empower a chemistry team designing and synthesizing high quality DNA-encoded and compound collection libraries, including leveraging external partnerships. Alongside this, your team will collaborate with Discovery Sciences and Therapeutic Area chemistry teams to establish priorities for compound libraries and off-DNA compound synthesis, provide expert insight to project chemistry, manage expectations and communicate progress. Other accountabilities:

* Collaborate with Discovery Sciences disciplines and engage with the AstraZeneca chemistry community to establish and lead science, technology and strategy developments.
* Develop yourself and your colleagues to maximise individual and team contributions.
* Enhance the external science and technology reputation of AstraZeneca chemistry through academic collaborations, peer-reviewed publication, external presentation of innovative results and involvement in external scientific communities.

We truly believe that everyone contributes with a unique set of competence. Your curiosity and passion for personal development combined with support from colleagues and other leaders, will ensure you maximise your skills, abilities and contribution.

Essential in this role:

* Engaging leadership with clarity of purpose, excellent communication skills and a passion for science, project delivery and personal and team development.
* Expertise in synthetic chemistry, including the design and synthesis of DNA-encoded and compound collection libraries, with an understanding of drug discovery and the external chemistry environment.
* Collaborative leader with the skills and behaviors to develop trusted, interdisciplinary partnerships that ensure alignment of priorities and inspire the delivery of ambitious capability developments.
* Ph.D. in synthetic organic chemistry with a minimum of 4 years of experience in a drug discovery unit or pharmaceutical company.

Experience of advanced and emerging automated chemistry technologies, external chemistry partnerships, academic collaborations and an active network of external contacts is a great plus.

Why AstraZeneca?
Ultimately, it's more than a job. We know that our work impacts people with serious conditions, many of whom have no other alternatives. That's what drives us - the potential to impact over one billion patients worldwide. Thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment.

So, what's next? If you're passionate about the possibilities of science to make a difference, welcome to join us!

We look forward to get to know you and invite you to submit your application as soon as possible, but no later than the 18th April, 2022.

For more information about the position please contact Clive Green, Executive Director Compound Synthesis and Management, at clive.green@astrazeneca.com.

Additional information:
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html
About iLAB - Innovation Lab: https://www.astrazeneca.com/r-d/our-technologies/ilab.html