Discovery Safety Scientist/Senior Scientist, In Vitro Biology

Are you a motivated cell biologist with experience of in vitro work in molecular biology, omics, high content cell imaging? Do you also enjoy working hands-on in the lab with a great group of colleagues by your side? If yes, this might be the next position for you!

Right now, we are looking for 3 highly engaged and enthusiastic cell biologists to join as a Discovery Safety Scientist or Senior Scientist, depending on your background and experience, and complement us in our In Vitro Safety group, which is part of Respiratory & Immunology, NeuroScience, Vaccines & Immune (RINVI) Therapies Safety, at AstraZeneca in Gothenburg, Sweden.

By joining the in vitro safety team in the RINVI safety group at AstraZeneca you will be exposed to a highly dynamic and challenging work environment that will allow you to adapt and expand your in vitro experience to application of safety challenges within the drug discovery process. You will have access to advanced in vitro technologies and be encouraged to work in an independent, science-driven manner. You will also join a diverse team of engaged and friendly scientists from a broad variety of backgrounds.

What you'll do:
Working in an industry-leading safety organization you will design and complete experimental strategies to predict, assess and mitigate target- and drug-related safety risks in drug discovery and development programs and develop mechanistic understanding behind (potential) safety concerns. You will propose, develop and integrate novel in vitro safety assays and technologies to drive our predictive scientific capabilities for drug safety, with a focus on the Therapeutic Areas Respiratory & Immunology, NeuroScience and Vaccines & Immune Therapies.

You will use your experience as a cell biologist to work independently and as part of a team. You will champion in vitro based science and technology innovations to develop our strategic capabilities including collaborating with other engaged scientists across the organization and with leading academic institutes, publish in high quality journals and actively contribute to scientific field networks.

Who you are:

The ideal candidates will have a passion for in vitro lab based experimentation and analysis and value the utility of early drug safety investigations. We are looking for someone with strong communication and collaboration drive, who can adopt a brave and forward thinking approach to drive our predictive in vitro safety assay design to support drug discovery and development projects.

Be encouraged and supported to think creatively in our dynamic environment. Here we are free from fear of failure, free to ask the right questions and make bold decisions.


Essential for the role:

* PhD in biology, biotechnology, toxicology or pharmacology or a related field.
* Strong background in mammalian cell biology and in vitro work in molecular biology, omics, high content cell imaging and other technologies such as western blot, ELISA, FACS.
* Experience of complex in vitro cell models, MPS systems or Spatial transcriptomics would be desirable.
* Experience in the culture of primary neurons, astrocytes and microglia, and human iPSC neurons is essential for one of the positions.
* Track record of scientific delivery, evidenced by impactful publications, establishing collaborations, delivering successful funding proposals.
* Strong communication skills: including presenting, manuscript preparation, influencing and building partnerships with internal and external research groups.

Why AstraZeneca?
With more than 2,800 employees from over 60 countries, our vibrant Gothenburg site is a truly inspiring place to work. Here, the history and future of scientific breakthrough come together. We believe that the diversity of our people is crucial to bringing new discoveries to life.

So, what's next?
If this sounds like the job and place for you - apply today!
We look forward to get to know you better. Send in your application as soon as possible, but no later than 5th September, 2022.
For more information please contact Paul Fitzpatrick, Associate Director - Respiratory & Immunology Safety Science, at paul.fitzpatrick2(at)astrazeneca.com.

Additional information
Our AstraZeneca Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Make a move to Gothenburg: https://www.astrazeneca.se/om-oss/verksamheten-i-sverige/goteborg/relocate-to-gothenburg.html
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html