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Arbetsbeskrivning
Do you enjoy working in the lab and have experience within formulation and analytical characterization of active pharmaceutical ingredients? Are you interested in developing liquid formulations for early in vivo studies? Do you enjoy to work collaboratively with and learn from highly motivated and skilled scientists? We are looking for you that are a formulation and analytical chemist with experience in the pre-clinical phase of drug development.
AstraZeneca is now seeking a Formulation/Analytical Scientist to join our Small Molecule Preformulation and Biopharmaceutical team within the Advanced Drug Delivery (ADD) function that is part of Pharmaceutical Sciences at AstraZeneca in Gothenburg, Sweden.
At AstraZeneca we turn ideas into life changing medicines and strive to continuously meet the unmet needs of patients worldwide. Working here means being entrepreneurial, thinking big, and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re the one we are looking for. Pharmaceutical Sciences at AstraZeneca delivers the therapies of the future through scientific leadership in drug delivery, design of synthetic routes, and manufacturing of Active Pharmaceutical Ingredients (API) and drug products. Our portfolio of projects spans traditional small molecules, peptides, oligonucleotides to RNA based therapeutics across AstraZeneca’s therapy areas. Advanced Drug Delivery (ADD) resides within Pharmaceutical Sciences with a mission to provide novel products to AstraZeneca’s clinical pipeline.
About the position
As a Scientist working in the pre-clinical development phase within ADD you will support drug projects from a formulation perspective, from the first in vivo studies to candidate drug nomination. You will focus on various small molecule projects and develop formulations and analytical assessments for PK, PK/PD studies, and toxicology studies. You will work as a member of pharmaceutical project teams, and in close collaboration with other analysts, formulators, solid state, biopharmaceutics experts at AstraZeneca.
Preferably, you should are experienced in formulation chemistry as well as in analytical chemistry and have previously been exposed to an industrial setting. You should possess an enthusiasm for laboratory-based work, be flexible and have a collaborative and problem-solving mind-set. We are looking for a scientist with good communication and planning skills, balanced with the ability to work independently. In addition, you will need a strong sense of responsibility, team work and delivery focus.
Responsibilities
• Support drug development projects with formulations for pre-clinical in vivo investigations.
• Perform essential characterization of the formulations e.g. content, impurity, pH and particle size measurements to support studies like stability, homogeneity etc.
• Generate, evaluate and report data clearly and reliably in accordance with current standard procedures.
• Give formulation/analytical support to scientific initiatives together with other specialists within these areas.
• Working as a member of cross-skilled drug development project teams.
Your profile
Essential Requirements
• MSc degree in a scientific discipline relevant to formulation/analytical science (e.g., chemistry, pharmaceutical technology, surface & colloid chemistry or equivalent qualifications).
• Basic knowledge of analytical methodologies such as spectrometry, separation science (U/HPLC) and physical particle characterization, i.e. particle size measurements.
• Understanding of principles and applications of Good Laboratory Practices (GMP/GLP).
• Ability to communicate in English both orally and in writing.
Desirable Requirements
• 3+ years of industrial experience of formulation work focused on small molecules in pre-clinical drug development phase.
• Profound knowledge within liquid based formulation science as well as analytical chemistry.
About the organisation
This position is a consultant assignment at AstraZeneca via QRIOS Life Science & Engineering in Göteborg for one year. During this time you will be employed by QRIOS Life Science & Engineering.
QRIOS employs curious experts in IT, Life Science and Engineering. We want to continue to attract the best employees, to continue to support our partners with the important competences you require. We are a recruitment and consulting company that is strongly inspired by those who never stop looking for new solutions. As we say, QRIOS MINDS GO FURTHER
Why AstraZeneca?
At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.