Head of DMPK

Are you an experienced leader with extensive DMPK experience? Would you like to apply your expertise to impact project delivery in a company that follows the science and turns ideas into life changing medicines? Join us in our thrive to discover future patient treatments!

Chronic degenerative diseases significantly affect life span and life quality. In Early Respiratory & Immunology (Early R&I) we are working to improve the lives for millions of people worldwide suffering from chronic respiratory and immunology diseases.

What you'll do

As a Head of DMPK, you will get the opportunity to build a dynamic, innovative and science focused department. Your leadership will have impact on the organization as well as strategies and science and you are a true role model who collaborates internally and externally to achieve innovation. You will report to Maria Belvisi, Senior VP, and have an impactful role in the Early R&I leadership team.

Your accountabilities include setting the direction and lead the DMPK science across the therapy area, across all therapeutic modalities. This includes securing adequate non-clinical DMPK and PKPD support to R&I programs across our three R&D sites in Gothenburg, Cambridge and Gaithersburg.

Your strategic and scientific accountabilities will include:

* Deliver predictions of human pharmacokinetics and target engagement with enough accuracy to allow project progression on clinical plans based on predicted DMPK properties
* Deliver biotransformation work non-clinical DMPK package to meet regulatory requirements
* Deliver pharmacokinetic characterization and understanding to support drug design and choice of drug modality
* Leading all aspects of processes and standards to ensure their appropriateness and guarantee compliance to all internal and external processes

Essential for the role

You hold a PhD within the DMPK area, which is complemented by extensive post-doc level experience, preferably within the Respiratory or Immunology areas. Your DMPK knowledge spans a wide range of drug therapeutic drug modalities e.g. small molecules, peptides, proteins, antibodies and nucleotide therapeutics. Furthermore, you are a recognised scientist with a strong track record of publications. Your thought leadership has been proven by innovative drug project delivery, alternatively by scientific leadership through academic excellence.

We believe that you possess:

* Ability to influence strategically and persuade tactfully, to acquire desired outcomes while maintaining effective and positive organizational relationships
* Proven history of building successful internal, as well as external, partnership and collaboration relationships, demonstrating cultural sensitivity and awareness
* Strong DMPK knowledge for a good understanding of in vitro and non-clinical DMPK models, assays and translational aspects
* Experience of leading teams and preferably department
* Conceptual, analytical and critical thinking

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial -finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we're opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

So, what's next!

Are you already imagining yourself joining our team? Good, because we can't wait to hear from you.

Welcome with your application no later than July 13.

Where can I find out more?

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