Head of DMPK Modelling & Simulation

Are you passionate about people, as well as drug development? Can you envision combining your Scientific Expertise with your people Management Skills? Join us in our thrive to discover future patient treatments!

At AstraZeneca, we believe in the potential of our people and you'll develop beyond what you thought possible. We make the most of your skills and passion by actively supporting you to see what you can achieve no matter where you start with us.

Chronic degenerative diseases significantly affect life span and life quality. In Early Respiratory & Immunology (Early R&I) we are working to improve the lives for millions of people worldwide suffering from chronic respiratory and immunology diseases.

We are now hiring a Head of DMPK Modelling & Simulation, within department of Drug Metabolism and Pharmacokinetics (DMPK) and the Early Respiratory, Inflammation and Autoimmunity therapy area. The position is placed at AstraZeneca's vibrant R&D site in Gothenburg, Sweden, one of AstraZeneca's three strategic science centers.

What you´ll do

This is a scientific and strategic role accountable for leading a team of scientists, all delivering into multidisciplinary project teams. You are expected to have experience, knowledge and insight in pharmacokinetic and pharmacodynamic properties of therapeutic molecules and be able to use these skills in making predictions of efficacious dosing. You will be part of Early R&I DMPK leadership team, where you will oversee and implement best-practice and process for DMPK project work as well as lead the DMPK functional review of the Early R&I portfolio. You are also expected to operate as a DMPK Project representative.

Your strategic and scientific accountabilities will include:

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Act as a line manager, ensuring a fair distribution of work amongst the team and see to that the team/section is constantly advancing through appropriate personal and team objectives
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Work through personal objective setting and ensure high performance of team members
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Make your team a great place to work through provisioning of individualized development opportunities and by role-modelling respectful and inclusive behavior
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As a member of Early R&I DMPK Leadership Team you are requested to be pro-active in anticipating the changing needs of the department, come up with new ideas, make proposals to keep the department active and scientifically forward-thinking
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Be up to date with the scientific literature relevant to drug design, pharmacology and PKPD and use this to influence the science performed in R&I
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Seek internal and external collaborators who share a passion for science to seize opportunities for advancing DMPK science, increasing the speed and probability of success for drug discovery projects

Essential for the role

You have a scientific background with strong interpersonal skills. In addition, an ability to engage and collaborate across boundaries with a problem-solving attitude and with focus on delivery.

You should possess basic PK modelling skills, understanding of disease biology and translational PK/PD. Furthermore, you master complex DMPK matters, and can link these to the impact on safety and efficacy.

In addition, you also possess:

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A Ph.D. in chemistry, pharmacy or related with a minimum of 5 years of experience in a drug discovery DMPK department within a pharmaceutical company, or equivalent experience
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Scientific in-depth knowledge in the DMPK field
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Excellent written and verbal communication skills in English
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Knowledge of the pharmaceutical drug discovery and development process
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Strong influencing, networking and leadership skills





Welcome with your application no later than 30th October 2020.



Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial -finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we're opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.



Additional information

Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html

Culture and atmosphere of the Gothenburg site: https://www.linkedin.com/feed/update/urn:li:activity:6496327311678410752/

Life in Gothenburg and Sweden: https://www.movetogothenburg.com/