Industrial PhD

We are now looking to fill an industrial PhD position in PET chemistry within a Marie Sklodowska-Curie Innovative Training Network.
AstraZeneca and the University of Aberdeenwill offer the PhD student a unique opportunity to gain world class knowledge and hands-on experience in various applications of medicinal chemistry and drug discovery at the forefront of biomedical research and development. The successful candidate will also participate in the network's training activities and work placements at the laboratories of the University of Aberdeen. The degree will be awarded by the University of Aberdeen.

Projects
The doctoral training positions advertised herein are to be filled at AstraZeneca R&D Gothenburg, Sweden in conjunction with the University of Aberdeen, UK (where the successful candidates will be registered for a PhD).
The research project will focus on the design of a novel radiotracer for the CCR2 receptor. The CCR2 receptor has been implicated in many disease states including diabetes. A PET tracer selective for CCR2 could potentially aid in the diagnosis of diabetes and as a means to assess treatment. This project will focus on the synthesis of appropriate moieties to allow PET labeling while retaing CCR2 affinity and subsequent in vitro evaluation. Some travel to AstraZeneca facilities in Stockholm may be required.
Tasks include
The successful candidates will work together with 11 other PhD students within the PET3D consortium and will be included in a network-wide training and secondment programme.
- Assay development and screening for the identification of CCR2 ligands
- The synthesis of small molecules for testing and to serve as PET precursors
- The synthesis of F-18 labeled CCR2 labeled PET tracer and use of the tracer in animal experiments

Qualifications
A diploma and/or a master's degree in chemistry, medicinal chemistry, or chemical biology, preferably with a research project in organic synthesis
An excellent track record from previous studies, along with experience in organic synthesis or medicinal chemistry.
Fluent in the English language (spoken and written/proficiency level).

Other

In accordance with the Marie Sk?odowska-Curie actions mobility requirements, candidates are only eligible for this position when they have spent no more than 12 months of their main activity (work, study) during the last three years in Sweden.
For more information about the position please contact: Charles S. Elmore, at +46 (0) 722 135 480

Welcome with your application no later than July 7th, 2016.