Laboratory Engineer, GMP production of cell therapy

Cell Biologist / Laboratory Engineer, NextCell
Mesenchymal Stromal cells (MSC) are a revolutionary cell therapy for several severe and incurable diseases. NextCell’s umbilical cord MSC based drug candidate, ProTrans, is primarily used for treatment of autoimmune and inflammatory diseases. Currently, there are several ongoing clinical trials using ProTrans to treat Type-I Diabetes and COVID-19.
NextCell also operates Cellaviva, Scandinavia's largest stem cell bank of umbilical cord blood and umbilical cord tissue stromal cells for familial use. The umbilical cord is a rich source of young and viable stem/stromal cells that can be collected by non-invasive methods. The cells are harvested from the umbilical cord after birth, making valuable use of dispensable material.


Cell biologist - Stockholm, Sweden
NextCell Pharma is a small, research driven company searching for a careful, structured, detail-oriented person to develop and produce advanced cellular therapies. To produce quality therapeutic products, a large part of our research and development focuses on identifying the optimal characteristics of stromal cells, specifically how these characteristics modulate autoimmune or inflammatory responses. We also develop and optimize cell therapy production protocols and potency assays to produce indication specific therapeutic products. Our cleanroom facility neighbors Karolinska University in Huddinge.


Position Description and Responsibilities
Perform and analyze results from potency assays with MSC.
Develop and validate potency assays.
Process patient samples from clinical trials using ProTrans.
Participate in developing and producing new cell therapies.
Cleanroom work in line with NextCell Pharma ABs routines and quality system.

Applicant Requirements
Licensed biomedical analyst equivalent or higher.
Several years experience with culturing and processing cells and tissues.
Experience with performing and developing cell-based assays.
Previous experience with working according to Standard Operating Procedures in a Quality Management System.
Experience with immunoassays like Flow Cytometry and ELISA
Experience with MSC and hematopoietic progenitor cells.
Experience with software programs Excel, Word, Flowjo, and GraphPad Prism.
Ability to communicate comfortably (speaking and writing) in English.

Merits
Experience with production of ATMPs
Experience with working according to GMP, GDP and GCP

Branch: Life Science, Biotech, Pharmaceutical
Employment type: 100%, Permanent with a probationary period of 6 months
Title: Laboratory Engineer
Applications should be sent to info@nextcellpharma.com as soon as possible as recruitment will be performed on a rolling basis.