Leading lab-based Single-Cell Sequencing specialist

Are you an experienced scientist in the Next Generation Sequencing area and have leading expertise of single-cell sequencing technology? Do you want to apply this knowledge in a role that is connected to our wider mission to show what science can do? We have the position for you!

We seek a highly engaged lab-based Scientist to join the Next Generation Sequencing (NGS) & Transcriptomics team at AstraZeneca in Gothenburg, Sweden. You will contribute with your single-cell sequencing technology expertise (including transcriptomics, genomics, epigenetics) to drive our single cell sequencing strategy and delivery to drug discovery research projects that will enrich our understanding of drug pharmacology, target mechanisms, model systems, patients and disease.

This is a rare opportunity to join the Translational Genomics Department within our Global Discovery Sciences function, where we apply cutting edge NGS/transcriptomic technologies, Precise genome editing in vitro and in vivo functional genomics model systems and cell therapy expertise to the discovery and development of novel therapies.

We offer a highly rewarding scientific environment with ample learning opportunities and an expectation to publish new findings. There's no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.

What you will do:
This role for a leading Single-Cell Specialist in the NGS area, is a hands-on lab-based role with a focus on defining our single-cell sequencing strategy and capabilities, effective delivery, troubleshooting and putting ideas into action.

Our team is a collaborative group and you will support the supervision and mentorship of other scientists, ensuring that methods run expertly and accurately, developing and guiding the set-up of new techniques. Included in the role is also to nurture strong collaborative relationships with the project investigators, key partners, and data scientists to ensure the smooth running of projects.

Essential in the role:

* Candidates should have a Ph.D. degree or equivalent experience in a relevant scientific field
* At least 3-5 years hands on expertise of applying/developing single cell sequencing technologies, preferably with multiple platforms (e.g. plate, droplet and chip) and modalities (e.g. transcriptomics, genomics, genetics, cell-surface proteins).
* Hands on expertise with a broad range of Next Generation Sequencing /Transcriptomics technologies that can include HT-qPCR, RNA-Seq, DNA-Seq, epigenetic methods, spatial or long read technologies.
* This experience will cover all relevant aspects from hypothesis generation, through experimental design and execution, sample and library preparation, sequencing, data handling, post sequencing QC and trouble shooting.
* Strong evidence of experimental impact through a track record of High-Impact or High-Quality publications, internal and external presentations.

Desirable in the role:

* Experience in one or more of the following areas - novel method development, assay miniaturization, liquid handling/automation.

Why AstraZeneca in Gothenburg?
Our Gothenburg site is one of AstraZeneca's three strategic science centers. We thrive in a multinational environment working cross-functionally across the globe with AstraZeneca colleagues as well as academic and industry partners. Our way of life is to develop a working environment that furthers collaboration, openness and innovation. Therefore, we have built space for meetings, socializing and relaxation, where spontaneous meetings can give birth to new innovations.

Does this sound like the next challenge for you? If so, you are welcome to join us at AstraZeneca!

We look forward to your application no later than 9th April, 2021.

For more information about the position please contact Graham Belfield at +46 708 808733 or Graham.Belfield@astrazeneca.com

Additional information
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html