Molecular Biomarker Scientist to AstraZeneca

Are you a hard-working and curious Biomarker Scientist who wants to join a team working with outstanding science that have a direct impact for the patients? Do you also want to contribute to our larger purpose with excellent colleagues by your side working in a collaborative, global environment? If yes, we might have the position for you!

In the role as Molecular Biomarker Scientist you'll play an important part in our Early R&I Translational Science and Experimental Medicine (TSEM) organisation. Within TSEM, we are working in an open environment with a strong science focus. Our work bridges the science with clinical development and our mission is to understand disease mechanisms at the molecular level, identify the most effective target and the right patient population. This in order to close the gap between bench science and bedside clinical practice.

The position will be based in one of our three AstraZeneca TSEM locations; Gothenburg (Sweden), Cambridge (UK) or Gaithersburg (US). This is the place to go beyond discovery - we think holistically about patients and are always learning from those living with diseases. Welcome to join us!

What you will do:
One of our key remits is the development of biomarkers to drive patient segmentation, demonstrate target engagement, guide dose selection and bridge to clinical outcome. As a Molecular Biomarker Scientist, you have significant experience in the invention and discovery of novel biomarkers.

You are accountable for discovery and functional validation of respiratory and inflammation precision medicine genetic and molecular biomarkers, as well as their further development as clinically meaningful measures. You will be recognized as a specialist in molecular biomarkers, seen as point of reference for others and function as a key member of development teams. As well as drive innovation in the Biomarker Discovery team through internal scientific development and external collaborations. You will raise AZ scientific visibility through publishing scientific papers and presenting data at conferences.

With a broad understanding of opportunities and limitations of NGS (next-generation sequencing) technologies in the context of biomarker discovery, and experience of DNA and RNA manipulation for biomarker discovery, you will push our work forward. You are responsible for the design, execution, interpretation and reporting of molecular based biomarker studies and will validate knowledge extracted from big Omics-datasets through considered and robust biomarker analysis of human tissue.

Essential in the role:

* PhD or equivalent within relevant field. Post-doc experience is desirable.
* Direct experience in biomarker invention and implementation in biopharmaceutical clinical study.
* Dept understanding of drug discovery and a track record of delivering state-of-the-art biomarkers to projects in discovery and/or development setting.
* Proven experimental drive and background in basic science related to respiratory and/or immunology research.
* Technical expertise in specific biomarker discovery and analysis platforms including but not limited to - genomics, transcriptomics, epigenomics, NGS, proteomics, etc.
* Detailed experience and knowledge of the biological basis for patient segmentation and precision medicine.

The successful candidate is also a truly motivated scientist with a passion to make a difference for patients all over the world. Along with this we see you as a person who enjoys team work and networking and is a good colleague to all. This goes hand in hand with your strong problem-solving and communication skills.

Why AstraZeneca?
Thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment. Ultimately, it's more than a job. We know that our work impacts people with serious conditions, many of whom have no other alternatives. That's what drives us - the potential to impact over one billion patients worldwide.

So, what's next! If you want to be a part of pushing the boundaries of science together with us - apply today! Welcome to send us your application as soon as possible, but no later than 15th August, 2021.

For further details around this position you are welcome to contact the recruiting manager Zach Brohawn on email: zach.brohawn(at)astrazeneca.com

Where can I find out more?
Follow AstraZeneca on LinkedIn: https://www.linkedin.com/company/1603/
Follow AstraZeneca on Instagram: https://www.instagram.com/astrazeneca_careers/?hl=en
Read more about BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html

NOTE - Due to summer vacations the communication may be a bit delayed, but we will get back with an update on your application later on in August at the latest. Thanks in advance for your patience!

Competitive salary and benefits package on offer.