NGS Biomarker Scientist

Are you a scientist with Biomarker Discovery experience ready for your next step in your career? At AstraZeneca, we believe in the potential of our people and you’ll develop beyond what you thought possible. We make the most of your skills and passion by actively supporting you to see what you can achieve no matter where you start with us!
To further strengthen our expertise and capacity we are currently recruiting an outstanding scientist within Early Respiratory and Immunology. Do you want to join our team?
Main Duties and Responsibilities
Our Early RIA Translational Science and Experimental Medicine (TSEM) department is an agile environment with a science focused culture. Our mission is to understand disease mechanisms at the molecular level, identify the most effective target and the right patient population and close the gap between bench science and bedside clinical practice.
One of our key aspects is development of biomarkers to drive patient segmentation, demonstrate target engagement, guide dose selection and bridge to clinical outcome. As NGS Biomarker Scientist, you are responsible for the execution of NGS-based experiments seeking to increase disease understanding and identify novel precision and target engagement biomarkers.
You will:
Part take in the design and be responsible for the execution, interpretation and reporting of NGS studies.
Supporting the development of NGS technologies to enable the respiratory biomarker discovery platform.
Championing the training of NGS techniques to scientists with Early Respiratory and Immunology.
Be responsible for the daily routines in the NGS laboratory in Early Respiratory and Immunology.
Validate knowledge extracted from big omics-datasets through robust biomarker analysis in human tissue.
Drive innovation in Biomarker Discovery through internal scientific development and external collaborations.
Make AZ scientifically visible by publishing scientific papers and presenting data at conferences.

Essential Requirements
This is a role that requires a strong scientific background as well as excellent technical skills. You need outstanding team working skills and a history of successful collaboration. Furthermore, you are familiar with the drug discovery and development process from lead identification through to clinical trials.
MSc or PhD within relevant field.
Proven experimental expertise within the NGS field or extensive expertise in molecular biology techniques.
Good networking and interpersonal skills.
Understanding of relevant technologies and methods outside NGS along with scientific laboratory skills.

Desirable Requirements
Experience in pharmaceutical R&D.
Technical expertise in specific biomarker discovery and analysis platform including genomics, transcriptomics, proteomics, metabolomics, epigenomics, lipidomics, NGS, mass spec etc.
Experience and understanding of respiratory disease biology including understanding of molecular pathways and mechanisms
Experience and knowledge of the biological basis for patient segmentation
Familiar with biomarker invention and implementation

Respiratory is one of AstraZeneca’s main therapy areas. Our aim is to transform asthma and COPD treatment through inhaled combinations at the core of care, biologics for the unmet needs of specific patient populations, and scientific advancements in disease modification.
Our Respiratory research is mainly carried out at the dynamic AstraZeneca Research site in Gothenburg, Sweden. However, collaboration is a way of life for us. Extensive collaboration with our AstraZeneca colleagues in Cambridge UK, Gaithersburg, US, as well as numerous academic institutions and partners around the globe gives us access to a worldwide network of expertise and innovation.