NGS Molecular Biologist - Oligonucleotide therapies

Are you an experienced scientist with great expertise in Next Generation Sequencing and Molecular Biology? Do you want to use this expertise to contribute to the discovery of novel oligonucleotide therapies? We have an opening suitable for you!

Right now, we are looking for a passionate and hard-working Molecular Biologist with NGS skills to join our Drug Molecular Profiling - NGS & Transcriptomics team at AstraZeneca in Gothenburg, Sweden. You will contribute with your expertise in applying molecular biology and NGS expertise to the discovery of novel oligonucleotide therapies. In our Translational Genomics Department, we apply cutting edge NGS/transcriptomic technologies, precise genome editing in vitro and in vivo functional genomics model systems and cell therapy expertise to the discovery and development of novel therapies.

We continually push the boundaries of science to deliver medicines that treat diseases across our main therapy areas. Through our integration with Alexion, this now includes expanding the limits of scientific research to better understand rare diseases and to discover new life-changing treatments for them.

What you will do:
This role is for a Molecular Biologist with significant NGS expertise, which you will apply to the characterization and profiling of the effects of oligonucleotide treatments in in vitro and in vivo cellular assays and models in support of novel drug discovery projects.

Our team is a collaborative group and you will engage in the supervision and mentorship of other scientists, ensuring that methods run expertly and accurately, developing and guiding the set-up of new techniques. Included in the role is also to nurture strong collaborative relationships with the project investigators, key partners, and data scientists to ensure the smooth running of projects.

Essential for the role:

* Ph.D. degree or MSc with corresponding experience in a relevant scientific discipline.
* Hand on lab-based experience in utilizing advanced molecular biology RNA-sequencing techniques including Single Cell Transcriptomics or Spatial Transcriptomics.
* This experience will cover all relevant aspects from hypothesis generation, through experimental design and execution, large scale RNA and DNA extraction, sample and library preparation, sequencing, data handling, post sequencing QC and trouble shooting.
* Experience in the detection of nucleic acids in high throughput assays and approaches.

You should also have the ability to communicate, interact and collaborate with your direct team members, as well as. Alongside this, our ideal candidate enjoys working in an innovative, proactive, forward-thinking, project-focused and goal-oriented way and shares our excitement about the molecular biology RNA-sequencing techniques.

Highly desirable for the role:

* Working with laboratory automation / liquid handling systems, method and technology development and optimization.
* Hands-on laboratory experience running NGS platforms (Illumina, Oxford Nanopore etc).
* Sample Tracking by LIMS systems.

Why AstraZeneca?
It's our combination of curiosity and courage that drives us, inspired by the possibility of doing things that have never been done before. Empowered to step up, we free ourselves from fear of failure to dig deep into the biology of complex diseases and make bold decisions. Celebrating our successes and failures along the way.

So, what's next? If this sounds like your next challenge - welcome to join us at AstraZeneca!

We look forward to get to know you better and we need your application no later than 27th February, 2022.

For more information about the position please contact Graham Belfield at +46 708 808733 or Graham.Belfield@astrazeneca.com.

Additional information
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/
Make a move to Global Gothenburg: https://www.youtube.com/watch?v=c-Iqbb4aw38
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html