PhD position

Lunds universitet grundades 1666 och rankas återkommande bland ett av världens 100 främsta lärosäten. Här finns 41 000 studenter och 6 900 medarbetare i Lund, Helsingborg och Malmö. Vi förenas i vår strävan att förstå, förklara och förbättra vår värld och människors villkor.

The Faculty of Medicine is a part of Lund University, and is responsible for education and research within medicine and healthcare. Our academic programmes are closely linked with the healthcare system and are firmly anchored in the faculty’s strong research tradition. Our research spans a broad field within experimental preclinical research, near-patient clinical research and health sciences research. The Faculty of Medicine, with its 1,800 employees and 2,700 students in Lund and Malmö, is a knowledge-intensive meeting place for students, teachers and researchers from all over the world.



The Department of Experimental Medical Sciences mission is to perform molecular, cellular and integrative research at the highest international level and to train a new generation of successful scientists.

We study biological processes that govern normal human bodily functions that are involved in disease pathogenesis. Several of our research environments have been recognized as outstanding both at the national and European levels.

PhD project: The main aim of this thesis will be to establish and characterize an in vitro model of Parkinson´s disease that is based on patient derived reprogrammed neurons cultured on collagen hydrogel scaffolds. The cells will be functionally characterized using in vitro electrophysiology. The effect of cell phenotype and function of neurotrophic and anti-inflammatory factors will be tested and delivered using functionalized scaffolds with the aim to determine their therapeutic potential.

The project is part of BrainMatTrain, a four-year project, funded by the European Union Horizon 2020 Programme (H2020- MSCA-ITN-2015) under the Marie Sklodowska-Curie Initial Training Network and Grant Agreement No. 676408. The project focuses on the scale up, commercialisation and translation of functionalised biomaterial constructs for the treatment of Parkinson’s disease. The BrainMatTrain network comprises four academic institutes, two hospitals and two industry partners from seven European countries (Ireland, Austria, Sweden, France, Denmark, the Netherlands, and United Kingdom).

Eligibility: Students with basic eligibility for third-cycle studies are those who- have completed a second-cycle degree- have completed courses of at least 240 credits, of which at least 60 credits are from second-cycle courses, or- have acquired largely equivalent knowledge in some other way, in Sweden or abroad.

The employment of doctoral students is regulated in the Swedish Code of Statues 1998: 80. Only those who are or have been admitted to PhD-studies may be appointed to doctoral studentships. When an appointment to a doctoral studentship is made, the ability of the student to benefit from PhD-studies shall primarily be taken into account. In addition to devoting themselves to their studies, those appointed to doctoral studentships may be required to work with educational tasks, research and administration, in accordance with specific regulations in the ordinance.

Essential qualifications:

- Less than 4 years' full time equivalent research experience and not yet been awarded a doctoral degree (PhD).
- Resided less than 12 months in the country (Sweden) of the host/recruiting institution in the 3 years prior to selection.
- Good spoken and written English.
- Flexibility and ability to work in a team environment.
- Availability to travel nationally and internationally two to three times a year.

 Desirable qualifications:

- Undergraduate degree in Biomedicine, Natural Science, Neuroscience or similar topic
- Practical experience and theoretical understanding of electrophysiology is highly prioritized
- Experience with laborative work especially within cell culture, molecular biology, neurobiology
- Completed courses in stem cell biology and neurobiology including developmental neurobiology and neurodegenerative diseases
- Experience with statistics program, excel, graphical program (e.g. Adobe illustrator) and power point

Application must include: Applications (in English) should include a CV, certificates of examination grades, a 1-page motivation letter describing your research career goals, skills and experience, as well as two letters of recommendation.

Salary: As the position is funded by the Horizon 2020 programme of the European Union, the remuneration will be in line with the European Commission rules for Marie Sklodowska-Curie grant holders (Early-Stage Researchers, Initial Training Network). http://ec.europa.eu/research/mariecurieactions/index.htm

Type of employment: Limit of tenure, four years according to HF 5 kap 7

 

 



 



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