PhD student position in Organic Chemistry

Dnr: 313-607-10 PhD student position in Organic Chemistry with focus on computational and medicinal chemistry Project description Inherited and acquired modifications of chromatin and chromatin-related proteins, including acetylation, phosphorylation, and methylation, play critical roles in the regulation of gene expression, chromosome stability, genomic imprinting and stem cell development.The aim of this project is to improve the understanding of epigenetic signalling mechanisms and their importance for human health and disease through the discovery and distribution of chemical probes directed towards proteins implicated in epigenetic events.Specifically the candidate will work in a multidisciplinary team applying computational and medicinal chemistry to design and synthesize small organic compounds with the goal to obtain potent compounds that specifically target proteins involved in epigenetic signalling.The project is carried out in collaboration with the Structural Genomics Consortium at Karolinska Institutet in Stockholm.Application The application should include a letter of intent, certified curriculum vitae that includes information on previous education, copies of master or bachelor thesis if available, publications and other documents supporting your competence and suitability for the position.We also want e-mail address and phone number to two reference persons.The application may be written in English or Swedish.Requirements Prerequisites include either i) 240 ECTS credits of higher education studies of which 60 should be on an advanced level (Master level), or ii) 120 Swedish (old) credits (corresponding to 180 ECTS credits) of higher education studies if they were taken before July 1, 2007 or equivalent competence.Advanced courses in organic, medicinal and computational chemistry are qualifying.The successful applicant should have good ability to write and speak in English, creativity, power of initiative, independence and ability to collaborate.Evaluations will be based on results on University courses, quality of master or bachelor thesis, references, interviews and the letter of intent.A PhD education is 4 years (48 months) and the PhD student will get a formal position at the start of the project (Swedish ?doktorandanställning?).Up to 20 % as teaching assistant may be included in the position (then the position will be extended accordingly).Questions about the position will be answered by Prof.Applications will be discarded or, if the applicant so wishes, returned two years after the position has been filled.Documents sent electronically should be in MS Word or PDF format.