Post Doctoral Opportunity - Ref nr POSTDOC104

Cardiovascular and Metabolic Diseases (CVMD) Molndal, Sweden

Mechanisms of Endoplasmic Reticulum Calcium homeostasis and the role of Endoplasmic Reticulum stress in the loss of functional beta-cell mass in Type 2 diabetes.

We're currently looking for talented scientists to join our innovative academic-style postdoc programme which spans a wide range of disciplines and aligns with one of our therapeutic areas. From our centre in Mölndal, Sweden you'll be in a global pharmaceutical environment, working alongside our scientists who are contributing to drug discovery and development and be part of a much larger active global post doc community. You will be encouraged to pursue your own independent research in cutting edge laboratories, present at external meetings, and publish in leading journals. You will also be offered a comprehensive training programme.

What's more, you'll have the support of a leading academic advisor, who?ll provide you with the guidance and knowledge you need to ensure success of your projects and to help develop your career. This is an exciting opportunity, to work within a Pharmaceutical setting but maintaining a strong basic science focus aligned to drug discovery and development activities, making this an opportunity to make a real difference to the future of medical science.

Our vision is to be the number one company in cardiovascular and metabolic disease, saving lives and reducing morbidity through innovative science, collaboration and exceptional delivery.Our team is challenging conventional thinking by pushing the boundaries of science to create life-changing medicines that address multiple cardiovascular risk factors.

At the Diabetes department within CVMD iMED, a key strategic area of research is the regulation of pancreatic beta-cell mass and function, with the aim of discovering and developing novel targets with the potential to treat type 2 diabetes. The programme will give you the opportunity to apply novel tools to investigate the mechanisms by which endoplasmic reticulum (ER) stress contributes to the loss of functional beta-cell mass. It?s a key role in shaping our beta-cell strategy, and the future of the business, by identifying and characterising new pathways/targets, with opportunities to participate in, and gain knowledge of, the drug development process.

As a Postdoctoral Scientist ? Cardiovascluar and Metabolic Diseases, it?s essential that you have:

A PhD in a life science, and expertise in cellular and molecular biology
An excellent understanding of beta cell physiology and intracellular signalling, including proinsulin synthesis and cell death
Strong organisational, communication and interpersonal skills
An outstanding record of research, proven by publications in high-impact scientific journals

The following skills and qualifications are desirable:

To READ FULL JOBDESCRIPTION and TO APPLY:

http://jobs.astrazeneca.com/jobs/details/l1rPOST%20DOC%20104-post-doctoral-opportunity-cardiovascular-and-metabolic-diseases-cvmd-molndal-sweden