Postdoc Fellow: Cellular Senescence and Metabolism

Postdoc Fellow: Cellular Senescence and Metabolism

Do you have a passion for Science? Would you like to apply your expertise to impact a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you!

At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person.

About AstraZeneca in Gothenburg, Sweden

Our Gothenburg site is one of AstraZeneca's three strategic science centers. We thrive in a multinational environment working cross-functionally across the globe with AstraZeneca colleagues as well as academic and industry partners. Our way of life is to foster a working environment that nurtures, collaboration, openness and innovation. Therefore, we have created space for meetings, socializing and relaxation, where spontaneous meetings can give birth to new innovations. The unexpected ideas or thoughts that can come from a chat over something as simple as a cup of coffee or a stroll on our "walk and talk" meeting trail can be invigorating and insprational.

Summary of the group:

The successful Postdoc will be a part of AstraZeneca Early cardiovascular, renal and metabolic diseases group. In Early CVRM, we aim to slow, halt and ultimately reverse the progression of Cardiovascular Renal and Metabolic Diseases which affect millions of people every year, worldwide and remains a major unmet medical need. We investigate the drivers of disease and of disease progression through cutting-edge science, delivering innovative therapeutic approaches, to enable more patients to reach their treatment goals earlier. This position is in the Metabolism Bioscience department and will play a critical role in identifying new pathways and therapeutic targets for the treatment of metabolic diseases.

Main Duties & Responsibilities:

This project will focus on applying patient-centric methodologies, working with primary human cells and patient samples to identify new pathways and mechanisms to modulate liver and adipose tissue function. This will include:

* Designing and conducting experiments, both independently and with other scientists across several disciplines
* Interpreting the results and deciding on research project strategy
* Communicating the results both internally and externally, through presentations at meetings and conferences, and importantly publishing in peer reviewed journals

Education & Experience Requirements:

* A PhD in a life science area
* Expert knowledge in metabolic diseases, and liver and adipose tissue biology

Required Skills:

* The candidate must have expertise in basic cellular and molecular biology methods such as mammalian cell culture (preferably adipocyte and hepatocytes), and gene and protein expression analysis
* The candidate must have strong organizational, communication (spoken and written English), interpersonal skills and the ability to work well in a team
* Proven record of research, as shown by publications in reputable scientific journals
* Excellent technical writing and verbal communication skills

Desired Skills:

* Experience with cellular senescence and adipose tissue browning
* Experience with transcriptomics and proteomics techniques and large data set analysis
* Experience designing and executing in vivo experiments
* Experience working in cross-functional matrix teams

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we're opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

So, what's next?

If you're ready to bring new ideas and fresh thinking to the table, brilliant! We have a seat available, and we hope it's yours.

Where can I find out more?

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