Postdoc in Yeast Physiology

Information about the research
We are looking for a motivated post-doctoral research fellow to work on characterizing protein phase separation condensate formation in ribonucleoprotein granules and its effect on cell growth and fermentation properties. The candidate will: 1, isolate proteins can form phase separation condensates that colocalize with ribonucleoprotein granules in yeast; 2, use the large-scale fermentation infrastructure purify the candidate proteins and verify their phase separation properties using in vitro approaches; 3, investigate the effects of the condensates on cell growth and fermentation.

About the Division of Systems and Synthetic Biology
The Division of Systems and Synthetic Biology at the Chalmers University of Technology is one of the world leading research environments in systems and synthetic biology. Our research interests involve a wide range of activities from understanding the fundamental operational principles of metabolism and studies of metabolic diseases, to highly applied research directed towards development of new cell factories, e.g. used as next generation drug discovery and production platforms.The details of the division research activities may also be found here.

-The details of the departmental research activities may be found here.

Major responsibilities
Your major responsibilities are to carry out independent research in a critical and effective manner, to organise and manage data to a high standard, to regularly communicate results to your colleagues, and to disseminate your main conclusions to the scientific community in the form of meetings, conferences and peer-reviewed articles. You should be able to apply critical and creative thinking on a regular basis. Equally, you should be able to adopt an open-minded approach to work that allows integration of constructive feedback as well as the possibility of adapting your research direction based on new results. In addition, you should be proactive, capable of keeping up with the evolving technologies available and motivated to test and implement new protocols. You will also be expected to share in the responsibilities for keeping the lab and equipment in good condition.

For all postdocs at Chalmers
Your major responsibility as postdoc is to perform your own research in a research group. The position also includes teaching on undergraduate and master's levels as well as supervising master's and/or PhD students to a certain extent. Another important aspect involves collaboration within academia and with society at large. The position is meritorious for future research duties within academia as well as industry/the public sector.

Position summary
Full-time temporary employment. The position is limited to a maximum of one year. 

Qualifications
To qualify for the position of postdoc, you should have a PhD degree, generally should not be older than three years, in biotechnology/biological engineering or within a relevant field, with a strong background in yeast genetics and physiology.

You should be comfortable working with Saccharomyces cerevisiae. You should have experience on plasmid consturction, transformation; mRNA extraction, primer designing, and real-time polymerase chain reaction; purification of recombinant protein; western blotting; immuno-fluorescence staining; microscopy imaging; and cell culture. Previous experience with protein phase separation condensate formation is desirable, and experience with microbial cultivation in benchtop bioreactors is a plus.
You should have excellent team work and social abilities.

The candidate must also be hihgly proficient in spoken and writen English.


Chalmers continuously strives to be an attractive employer. Equality and diversity are substantial foundations in all activities at Chalmers.

Our offer to you
Chalmers offers a cultivating and inspiring working environment in the dynamic city of Gothenburg. 
Read more about working at Chalmers and our benefits for employees.

Application procedure
The application should be marked with Ref 20200434 and written in English. The application should be sent electronically and be attached as pdf-files, as below:

CV: (Please name the document as: CV, Surname, Ref. number) including:
• CV, include complete list of publications
• Previous teaching and pedagogical experiences
• Two references that we can contact.

Personal letter: (Please name the document as: Personal letter, Family name, Ref. number)
1-3 pages where you:
• Introduce yourself
• Describe your previous research fields and main research results
• Describe your future goals and future research focus

Other documents:
• Attested copies of completed education, grades and other certificates.

Please use the button at the foot of the page to reach the application form. The files may be compressed (zipped).

Application deadline: 30 October 2020

For questions, please contact:
Dr. Yun Chen, Systems and Synthetic Biology, yunc@chalmers.se

*** Chalmers declines to consider all offers of further announcement publishing or other types of support for the recruiting process in connection with this position. *** 
   



Chalmers University of Technology conducts research and education in engineering sciences, architecture, technology-related mathematical sciences, natural and nautical sciences, working in close collaboration with industry and society. The strategy for scientific excellence focuses on our six Areas of Advance; Energy, Health Engineering, Information and Communication Technology, Materials Science, Production and Transport. The aim is to make an active contribution to a sustainable future using the basic sciences as a foundation and innovation and entrepreneurship as the central driving forces. Chalmers has around 11,000 students and 3,000 employees. New knowledge and improved technology have characterised Chalmers since its foundation in 1829, completely in accordance with the will of William Chalmers and his motto: Avancez!