Postdoctoral Fellow: Developing new strategies for cell therapy

Gothenburg, Sweden



Would you like to combine the freedom and passion of driving your own research vision with the resources available in an industry setting?

Then join AstraZeneca Cell Therapy in our mission to develop new treatment ideas! Together we will improve the therapy standard in areas of high unmet medical need.



About the Opportunity:

This is an opportunity to join the newly established Cell Therapy department and work at the cutting edge of next generation medicine research.



The Cell Therapy department is a group of passionate researchers, dedicated to innovation and the advancement of science. We focus on pre-clinical research with the goal of bringing novel treatments across multiple disease areas, spanning from cardiovascular malignancies, through metabolic disorders to inflammation.



We will support you in developing a new, proof-of-concept modality for rare Inborn Error of Metabolism (IEM) diseases, such as Phenylketonuria (PKU). The project aim is to replenish the missing enzyme, for example Phenylalanine-4-hydroxylase (PAH), using a suitable cell type for delivery.



As a Postdoctoral Fellow you'll work with peers and professionals from diverse backgrounds, who will foster your scientific freedom. You will own the project, independently design the experiments and drive the execution of your vision. You will be supported by three internal scientific mentors, as well as a world-class external academic mentor, aligned to your project.



We will provide you with the resources required to optimally finalize your work, including proprietary techniques, modern equipment, reagents and in vivo work facilities. You will assess and present data to support project progression, sharing your findings at research conferences and in publications. Through this you will establish valuable networks which will support your research and future career development.



Qualifications, Skills & Experience:



Essential Requirements:

* PhD in Cell Biology, Molecular Biology, Genetics or a similar field;
* Hands-on experience with in vitro cell culture, particularly pluripotent stem cells and/or hematopoietic stem cells;
* Broad laboratory experience and meticulous scientific knowledge;
* A track record of publications in peer-reviewed scientific journals;
* Outstanding work ethic (discipline, perseverance and dedication);
* Creativity, proactiveness, being a forward-thinking scientist and a team-playing colleague with a passion for science.



Desirable Requirements:

* Hands-on animal work and experience using in vivo mouse models.



About AstraZeneca:

AstraZeneca is a global, science-led, patient-centred biopharmaceutical company focusing on discovering, developing, and commercialising prescription medicines for some of the world's most serious diseases. But we're more than a global leading pharmaceutical company. At AstraZeneca, we're dedicated to being a Great Place to Work and empowering employees to push the boundaries of science and fuel their entrepreneurial spirit.



About the Postdoc Programme:

Bring your expertise, apply your knowledge, follow the science, and make a difference. AstraZeneca's Postdoc Programme is for self-motivated individuals looking to deliver exciting, high-impact projects in a collaborative, engaging and innovative environment. You'll work with multidisciplinary scientific teams from a diverse set of backgrounds and a world-class academic mentor specifically aligned to your project. Our postdocs are respected as specialists, encouraged to speak up, and be supported to share their research at conferences, publish papers, achieve their goals and make a difference to our patients.



This is a 3-year programme, with an initial 2-year period and 1-year merit-based extension.

Where can I find out more?

For more information about the position and the project please contact project co-supervisor: Aleksandra Sienska (Aleksandra.sienska(at)astrazeneca.com) or read more:



About our Biopharmaceuticals R&D site

About the Postdoc Program

About AstraZeneca in Gothenburg



Are you already imagining yourself joining our team? Good, because we can't wait to hear from you!



Advert Opens: October 5th 2022

Advert Closes: November 9th 2022