OBS! Ansökningsperioden för denna annonsen har
passerat.
Arbetsbeskrivning
Postdoctoral fellow UCMR Umeå Centre for Microbial Research (UCMR; www.ucmr.se) was recently awarded a Linnaeus Grant from the Swedish Research Council for research on infectious diseases.Postdoctoral Position Intracellular survival mechanisms of Francisella tularensis Francisella tularensis is a highly virulent bacterium and the etiologic agent of tularemia.The disease occurs in a wide variety of mammals.The bacterium is transmitted to humans by various means, including bites from infected vectors and inhalation of infectious aerosols.The disease is rather common in the Nordic countries.While many of the molecular mechanisms of Francisella infections are largely unresolved, it has been established that the ability to survive and multiply in macrophages is essential for its virulence.The project will elucidate virulence factors of F. tularensis that allow multiplication in macrophages and also identification of factors that are unique to the highly virulent subspecies tularensis.Specifically, we have previously identified that strains of the subspecies are highly resistant to reactive oxygen species and the project will address the molecular mechanisms responsible for this ability.Most of the relevant methods are already established.We are looking for a highly motivated applicant with a PhD in microbiology and with expertise in molecular biology.Prior experience in working with cell infection models, animal models or bacterial gene regulation is a plus.For more information contact Prof.Successful candidates for the postdoctoral should have earned a PhD degree in fields relevant for the position.To qualify for the postdoctoral position should the applicant's PhD degree not be older than 3 years.Complete application should include: * Introductory letter with a statement of research interest * CV * A list of publications * Names and contact details of two persons willing to act as references Applications will be discarded or, if the applicant so wishes, returned two years after the position has been filled.Documents sent electronically should be in MS Word or PDF format. See complete advert: www.jobb.umu.se