Principal Scientist - Oligonucleotide Chemistry

Are you an experienced and passionate scientific specialist within Oligonucleotides and have a passion for research and development of Oligonucleotide Therapeutics? Do you wish to impact and flourish in an excellent team where you will have the opportunity to further exploit our drug discovery platforms? If yes, welcome to us at AstraZeneca!

We are looking for a motivated Scientific Specialist (Principal Scientist, high expertise level) with enthusiasm, expertise and experience in Oligonucleotides to join the Oligonucleotide Chemistry team within the Oligonucleotide Discovery Department at AstraZeneca in Gothenburg, Sweden. The department is part of the broader Discovery Sciences R&D organization.

AstraZeneca is committed to the development of next generation innovative medicines and is focused on expanding the use of oligonucleotides and molecular conjugates thereof, in the treatment of diseases across therapy areas. As an expert and member of the Oligonucleotide Medicinal Chemistry team you will have a key role to influence the strategy as well as to develop and lead the science in the field to expand the use of therapeutic oligonucleotides in drug projects within AstraZeneca.

Join a place built on innovation and creativity where different views and perspectives are welcomed and valued.


What you will do:
This is a Senior Scientific role for a specialist within the field of Oligonucleotides, where you will work as an expert within oligonucleotide medicinal chemistry and contribute to shaping the future of our therapeutic oligonucleotide build, identifying opportunities to innovate in the interface between oligonucleotide chemistry and conjugation to other chemical modalities. You will be a role model and support scientists in oligonucleotide medicinal chemistry by advising and challenging them and providing expert knowledge and interpretation of complex data.

Recommend and champion new innovations that enable the Oligonucleotide Discovery department to meet its overall objectives, as well as influence across disciplines in the drug project core teams to ensure state of the art approaches in oligonucleotide medicinal chemistry are used to answer the scientific hypotheses. We also want you to demonstrate scientific leadership through high quality publications, conference presentations and by building networks with key opinion leaders and academic groups.

Essential in the role:
Our team is a collaborative group working together for a greater goal and by showing self-awareness of training needs, including leadership development, being a strong team member and an encouraging colleague, you will be successful in this role. Furthermore, you are a scientifically critical and curious individual who has the ability to operate effectively in a multi-disciplinary research environment and take own initiatives.

You also have:

* PhD in Organic Chemistry and a post-doc experience or minimum 5 years of professional experience in pharmaceutical industry or academia.
* Expert knowledge and significant experience in oligonucleotide medicinal chemistry including IP strategies.
* Great knowledge in biological processes enabling the design of effective oligonucleotide ligand conjugates.
* Substantial track record of innovation and milestone delivery in oligonucleotides drug discovery projects across phases.

We truly believe that everyone contributes with a unique set of competence. Your curiosity and passion for personal development combined with support from colleagues, mentors and leaders, will ensure you improve your skills, abilities and contribution.

Why AstraZeneca?
With more than 2,800 employees from over 70 different countries, our vibrant Gothenburg site is a truly inspiring place to work. Here, the history and future of scientific breakthrough come together. We believe that the diversity of our people is crucial to bringing new discoveries to life.

So, what's next? If this sound like your next challenge and a good workplace for you - please apply today!

We look forward to your application and getting to know you better, but please remember to send it to us no later than August 13th, 2023.

For more information about the position please contact Anders Dahlén at +46 31 706 4842 or anders.dahlen(at)astrazeneca.com

Additional information:
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/
Make a move to Global Gothenburg: https://www.youtube.com/watch?v=c-Iqbb4aw38

Note: Due to Swedish summer vacation period, the screening process may take a bit longer than usual. Please bear with us and we will get back to you as soon as possible when we are back in August.