OBS! Ansökningsperioden för denna annonsen har
passerat.
Arbetsbeskrivning
As a research assistant you will be responsible for performing the in-situ analysis of biological tissue samples from collaborators and customer projects. You will support all aspects of the process from laboratory work with the tissue sections, to fluorescent microscopy of the tissue samples, and image analysis, to ensure the highest quality of results are reached. This work will be in close collaboration with expert scientists within spatial single cell analysis and gives you the possibility to participate in high profile cutting edge biological and disease-related research projects from Pharma- and academic researchers.
You'll have a proven track-record of using and optimizing/troubleshooting molecular biology protocols, as well as a broad understanding of molecular biology techniques. You will also interact closely with colleagues across various departments in both Stockholm and San Francisco.
What you will be doing:
Performing the in situ assay on tissue sections on microscope glass slides
High throughput fluorescent microscopy imaging of the processed tissue samples, and image data pre-processing
Participate in troubleshooting of assays and microscope instruments.
Optimization studies of protocols for specific tissue samples.
Deliver pre-processed image data to and work closely with computational biologists for image data analysis
Maintain relevant documentation for record keeping related to the projects
Recurring QC of reagents and samples may be included
You will learn all aspects of the technology and the workflow and may participate in some of these aspects, including probe and primer design, image analysis, data analysis, communication with collaborators and customers, presentation of data internally and externally, etc.
To be successful, you will need:
MSc, ore equivalent, in Biomedical sciences / Molecular Biology / Biochemistry, or similar field
Good wetlab experience with molecular biology techniques, including immune-staining and/or in situ hybridization techniques on cells, preferably tissue sections (FISH, RNAscope, in situ hybridization,...)
Fluorescent microscopy experience (confocal or standard epi-fluorescence)
A very good understanding of molecular biology techniques related to nucleic acid analysis
Excellent problem-solving and troubleshooting skills
Additionally, we’d like to see:
Tissue handling experience (fresh frozen, FFPE, cryosectioning, antigen retrieval,...)
Strong organizational skills and ability to plan and structure your work
Excellent interpersonal skills, including written and oral communication in English
Ability to work in a fast-paced and quickly changing environment
It would also be advantageous if you had:
Work experience from similar positions in academia and/or industry
Experience with image analysis using relevant SW (e.g. CellProfiler, ImageJ)