Research assistant in Hematopoietic Stem Cell Biology Laboratory

Do you want to contribute to top quality medical research?
We are looking for a highly motivated and talented research assistant to support research projects in the lab of Professor Sten Eirik Jacobsen (https://ki.

se/en/medh/sten-eirik-w-jacobsen-lab-hematopoietic-stem-cell-biology-group). The position and corresponding research projects are focused on modelling of normal and malignant hematopoiesis and hematopoietic stem cell biology in genetically modified mouse models, and will be funded by existing grants.

Your mission
About the research labs

The Jacobsen lab comprises an international collaborative team focused on understanding at the single cell level the cellular and molecular pathways governing the earliest fate decisions in normal hematopoiesis [1-4] and how these are dysregulated in hematologic malignancies [5-9]. This is studied in mouse models, as well as in relevant patients. Key technologies applied towards these research questions include high-throughput DNA and RNA sequencing including single cell analysis, genetic fate-mapping using next-generation-sequencing technology, flow cytometry, mouse genetics and various in vitro and in vivo stem cell assays.

Job description

The work will be conducted under the supervision of Professor Sten Eirik Jacobsen. The position is focused on supporting studies aimed at unraveling normal cellular and molecular pathways governing lineage commitment from hematopoietic stem cells and malignant transformation. Projects will be pursued in part at the Center for Hematology and Regenerative Medicine (HERM; http://ki.se/en/medh/herm), and in part at the Department of Cell and Molecular Biology (CMB; http://ki.se/en/cmb/startpage). The Jacobsen lab also have close interactions with other world leading research groups, and the recruited candidates will benefit from interactions in this highly collaborative network

All projects largely utilize mouse models of normal and malignant hematopoiesis but also require access to relevant patient material. The position will be directed towards supporting investigators with their experiments. In addition to the entry requirements, the candidate will be responsible for organizing common lab resources, such as equipment, reagents and lab infrastructure.

Your profile
Requirements

- A M.S. degree or higher in biology
- Extensive experience working with mouse models of hematopoiesis
- Extensive experience with procedures on mice including tail vein injection, intra-bone injection and intra-bone aspiration
- Experience in documentation and storage of research data
- Experience with administrative system for tracking and reporting mouse usage
- Excellent interpersonal and communication skills
- Strong language skills, including ability to speak and write English fluently

Desired

- Ability to perform and analyse flow cytometry
- Strong organizational skills to plan experimental bench-work
- Experience with administrative systems for tracking and charging lab orders
- Emphasis will be placed on personal qualities such as responsibility, flexibility, teamwork and ability to solve problems

What do we offer?
A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site.

Location: Flemingsberg

 https://ki.se/en/about/choose-to-work-at-ki-ten-reasons-why





Application
Application process

An employment application must contain the following documents in English or Swedish:

- A complete curriculum vitae
- A personal letter, including motivation for the position
The application is to be submitted through the Varbi recruitment system. Welcome to apply at the latest 27/4-22 

Permanent position is initiated by a six months trial period.

Want to make a difference? Join us and contribute to better health for all