Research Scientist Precise Genome Editing, AstraZeneca Gothenburg

Job description
At AstraZeneca we use scientific excellence as our foundation for driving success in our drug discovery pipeline. We underpin this with strong collaboration, clear direction and a focus on applying cutting-edge research to support drug discovery.

An exciting opportunity is now available to join the Precise Genome Editing team within Discovery Sciences, which has responsibility for the generation of novel genome editing technologies to support projects in all phases of the drug discovery pipeline. We have a focus on target identification, target validation, disease model generation and the therapeutic use of stem cells. We are seeking a scientist to join our team where the role will focus on generating genetically engineered mouse and cell models. This is a consulting assignment at AstraZeneca in Gothenburg.

Responsibilities
The role
Leveraging your strong knowledge and experience in genome editing you will have the opportunity apply your knowledge to gene therapy projects. This includes design of genome editing strategies, implement them using techniques including CRISPR/Cas9 and to validate the results. The role is focused on conducting laboratory-based activities, applying your knowledge and skills to drive project delivery and scientific innovation, participating actively in problem solving and working globally with Astrazeneca colleagues and collaborators.

It is essential to have good social and communication skills, be collaborative and a strong team player and be an innovative thinker. Candidates should be able to work independently, take own initiatives and have a positive, goal oriented and problem-solving attitude. Good organisational, data management and documentation skills are required, and you should be comfortable in presenting your results. English language is required, both spoken and in writing.

Tasks
Perform in vivo genetic manipulation and validation of engineered mouse models
To assist in the design and implement delivery tools for genome editing-based strategies to generate in vitro and in vivo models
To improve the efficiency of genome editing in vivo


Qualifications
Essential skills for the job:
Proficiency in ‘hands on’ in vivo work and delivery of reagents
Strong knowledge and experience with core molecular biology techniques
Experience with cell culture, preferable to have knowledge of primary cell culture

The following skills are highly desirable but not essential
Expertise with CRISPR based editing and NGS analysis of genome editing outcomes

Minimum experience
You should hold a degree or have significant relevant experience working in with small animals and a precise genome editing / molecular biology environment.

For us, it is important that all competence and skills in the labor market are utilized. We welcome all applicants and strive for diversity.

Application
2021-09-16, selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible.

For more information: Kerstin Karlsson, kerstin.karlsson@randstad.se

About the company
Randstad Life Sciences specializes in the field of science and is part of Randstad, the world leader in recruitment and consulting with operations in 38 countries. With this global network, in combination with our strong local foundation, we can offer a wide range of varied and developing assignments and jobs for you who are a specialist in life science. Our mission is to help you reach your true potential with your career in focus!