Research Scientist – Protein Expression Team

At AstraZeneca we use scientific excellence as the foundation to drive success of our drug discovery pipeline. Such excellence stems from strong collaboration, clear direction and a focus on applying cutting-edge research to support drug discovery.
An opportunity is now available for a highly motivated Research Scientist to join the Protein Expression Team within the Discovery Sciences Innovative Medicine (IMED) Biotech Unit in Gothenburg, Sweden. Leading from the bench, you will apply proven skills in molecular biology, recombinant protein production, a passion for investigating scientific questions, combined with strong team working ethics, to drug discovery projects. You will join our team whose remit is to support IMED projects globally with delivery of impactful recombinant protein reagents used for disease target identification and validation right through to clinical candidate evaluation.
As part of a team within the Discovery Sciences organisation, you will be working within a vibrant scientific environment to support drug discovery. We push scientific advances in small molecules, oligonucleotides as well as other emerging technologies, always with a view to providing medicines to improve patient care. The Discovery Biology Department of Discovery Sciences is responsible for the generation of novel reagents and assays to support projects in the drug discovery pipeline from target discovery all the way to clinical candidate.
Main Duties & Responsibilities
This is a lab-based role, generating bespoke molecular biology and protein reagents to support projects in all phases of the discovery process. The role involves application of leading molecular biology techniques to design and make expression constructs, producing recombinant proteins that impact projects, as well as troubleshooting.
Essential Requirements


BSc/MSc in Molecular Biology, Biotechnology, Biochemistry or a related discipline
Substantial expertise in molecular biology using a variety of modern techniques (Golden Gate, Gibson assembly or similar techniques)
Experience in design of DNA construct for recombinant protein production
Experience of automation of molecular biology work flows
Independent analysis and evaluation of complex data and delivery of data to agreed timelines
 

Desirable Requirements


Demonstrable experience in common methodologies for recombinant protein expression such as transient transfection of mammalian cells and baculovirus infected insect cells
Excellent communication skills and an ability to operate effectively in a multi-disciplinary research environment
Experience of automation of molecular biology work flows
Excellent problem-solving skills
 

If you are interested, please apply now!