Research Scientist – Translational Genomics In Vivo Physiology

We have an exciting opportunity for a Research Scientist to join Discovery Sciences’ Translational Genomics Group. We are seeking a scientific and technical specialist in the animal in vivo physiology field holding a Ph.D degree in a relevant scientific discipline or a first degree and significant relevant experience in drug discovery. Experience in metabolic phenotyping platforms and analysis of metabolic function in mouse models, molecular biology expertise and a working knowledge of the latest precise genome engineering tools both in vitro and in vivo with expertise in the generation and characterization of transgenic animal models and generation and use of viral vectors for in vivo genetic engineering is highly requested.

For further details around this consulting position (starting asap) you are welcome to contact Jenny Lundkvist at jenny.lundkvist@poolia.se.

Om tjänsten
The Discovery Sciences, Translational Genomics department is looking for an research scientist to be part of our in vivo physiology discipline within the Transgenic Models team. This position is based at the AstraZeneca R&D site in Gothenburg, Sweden and we are seeking a scientific and technical specialist in the animal in vivo physiology field. As a successful candidate you are experimentally focused, with strong troubleshooting skills and adept at putting ideas into practice. You will perform experimental strategies and make significant contributions to the practical delivery of projects in compliance with AstraZeneca corporate responsibility policies and relevant safety standards and of central importance is experience with murine in vivo experimentation. You will have good social and communication skills, be collaborative and be a strong team player. Candidates should be able to work independently and have a positive, goal oriented and problem-solving attitude. Good organizational skills are required and you should be comfortable in presenting your results. Excellent English is required, both spoken and written.

Specific responsibilities:
•Perform studies within the in vivo physiology discipline with full engagement with stakeholders to ensure the discipline operates at the scientific forefront, using world leading technologies and infrastructure to support all core disease areas
•Ensure that studies are conducted with quality, dedication and data delivered according to stipulated time lines and project requirements
•Compile, interpret, present and discuss data with key project teams and stakeholders
•Actively promote the in vivo physiology discipline activities to ensure visibility in the wider AstraZeneca organization
•Hands on activity in the lab when required for timely project progression

Vem är du?
The following skills would be an advantage:
•Experience in metabolic phenotyping platforms and analysis of metabolic function in mouse models e.g. performing indirect calorimetry and intraperitoneal glucose tolerance tests (IPGTT) to diagnose metabolic function in genetically-engineered mice, phenotyping platforms such as hyperinsulinemic-euglycemic clamps.
•Molecular biology expertise and a working knowledge of the latest precise genome engineering tools both in vitro and in vivo.
•Expertise in the generation and characterization of transgenic animal models
•Generation and use of viral vectors for in vivo genetic engineering

Minimum Requirements – Education and Experience:
You should have a Ph.D degree or corresponding experience in a relevant scientific discipline with experience in drug discovery or, alternatively, a first degree and significant relevant experience in drug discovery.

Om verksamheten
At AstraZeneca, we turn ideas into life changing medicines and strive to continuously meet the unmet needs of patients worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.


Are you ready to bring new ideas and fresh thinking to the table? Brilliant!
We have one seat available and we hope it’s yours.