Researcher

Kort beskrivning av företaget:
The University of Gothenburg tackles society's challenges with diverse knowledge. 37 000 students and 6 000 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.


Titel: Researcher

Beskrivning av arbetsuppgifter:
A position as a Researcher is immediately available in Clausen laboratory at the Sahlgrenska Academy, Gothenburg University, Sweden. Dr. Clausen's research group is interested in elucidating the molecular mechanism of genome instability and DNA repair. In particular, we are interested in understanding how DNA lesions and mutations are generated and are being repaired on a genome-wide, strand specific scale at single nucleotide resolution level. The group will use interdisciplinary approaches to map and characterize DNA lesions and mutations in yeast, human cells and in patients with genetic diseases or cancer. Clausen AR et al. Tracking DNA replication in vivo using ribonucleotides. Nat. Struct. Mol. Biol. 2015; 22: 185-91. PMID: 25622295. Clausen AR et al. Structure-function analysis of ribonucleotide bypass by B family DNA replicases. Proc. Natl. Acad. Sci. U S A. 2013; 110(42): 16802-7. PMID: 24082122. Clausen AR et al. Ribonucleotide incorporation, proofreading and bypass by human DNA polymerase delta. DNA Repair (Amst). 2013; 12(2): 121-7. PMID: 23245697. Job assignments: To handle, process, analyze, interpret and visualize our Next-gen sequencing data. Script writing to facilitate the analysis of our data.

Beskrivning av kvalifikationer:
PhD in genetics, biochemistry, bioinformatics or related areas. Excellence in research and communication. Expertise in large data handling, processing, analysis, interpretation and visualization using python, R or perl. Must be well organized and able to manage several projects with priority.