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Arbetsbeskrivning
AstraZeneca is a global, science-driven biopharmaceutical company. We turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. Here, we see the impact of our collective ideas and expertise, and the power of science to deliver them.
Pharmaceutical Sciences is a department within AstraZeneca Biopharmaceutical R&D. The Pharmaceutical Sciences' mission is to transform molecules into investigational medicines, meeting the unmet needs of future patients. Advanced Drug Delivery (ADD) is a department in Pharmaceutical Sciences. Our portfolio of projects spans traditional small molecules, proteins, oligonucleotides to RNA based therapeutics across AstraZeneca's therapy areas and our mission is to transform diverse modalities into investigational medicines.
We now seek a talented, motivated Scientific Director (Senior Principal Scientist (SPS)) to lead a preformulation team in Gothenburg, Sweden. The role will lead the proof-of-concept testing of new drug delivery technologies and help us drive the delivery of nucleotide based and peptide therapeutics, drug targeting, and local delivery for the Biopharmaceutical R&D portfolio. As ADD Preformulation Scientific Director (SPS) you will provide discovery support, input to compound and excipient design/selection as well as lead development and scale-up of formulations including analytical methods for clinical development, when the activities are conducted via partnering or outsourcing. You will also contribute to science strategy across ADD, Pharmaceutical Sciences and Biopharmaceutical R&D and be active in the science community in terms of presentations and publications
Your broad understanding of the discovery to launch drug development process, and excellent stakeholder management skills will ensure your ADD team provides first class scientific input and enabling insight to key functions across Pharmaceutical Sciences, Biopharmaceutical R&D as a whole, and beyond. You will be reporting to the Head of Advanced Drug Delivery and collaborate closely with other ADD teams located in Waltham/US, Cambridge/UK and Gothenburg/Sweden.
Essential Requirements
* Ph.D degree in a relevant scientific discipline.
* Industrial experience including with outsourcing/partnering in new modality formulation and/or analytical method development spanning discovery and early development
* Track record as a scientific leader, providing scientific challenge and direction to team members.
* Ability and proven track record in influencing drug substance and product design
* Knowledge of the overall drug research and development process from Discovery through to Launch, and an appreciation of how Pharmaceutical Sciences disciplines contribute to R&D and the broader business
* Understanding of the Astra Zeneca's disease areas to enable influencing of drug and drug product design.
* A leader of a product development scientific skill discipline including external visibility through publications, presentations and networking activities. Capable of and desire for continuing to develop self in this arena.
* Exposure to multiple disciplines in Pharmaceutical Development, CMC, and related functions
* Prior experience of leading, coaching and developing a team of scientists and experience of leading and managing change processes
* Innovative, with a passion for driving scientific excellence and a continuous improvement mind-set.
* Strong project management skills, with experience of managing external collaborations.
* Innovative, with a passion driving scientific excellence and a continuous improvement mind-set
* Ability to effectively communicate, network and build strong collaborative relationships with stakeholders across disciplines and cultures, internally and externally.
* Thorough understanding of principles, applications and management of Safety Health and Environment (SHE) and Good Manufacturing and Laboratory Practices (GMP/GLP).
Apply now to join us and help turn ideas into life changing medicines!
For more information about the position please contact Annette Bak, Head Advanced Drug Delivery at annette.bak@astrazeneca.com
We encourage you to send your application as soon as possible, as we will screen candidates on a continuous basis, but no later than August 31st, 2020.
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