Scientist Bioscience

Hays Life Science / Bioscience Scientist / Consultant Assignment / AstraZeneca / Gothenburg

Hays Life Science is looking for a Bioscience Scientist for a consultant assignment at AstraZeneca R&D Gothenburg.

For the interested candidates, please apply before 2nd August at latest.

Scientist, R&I Research and Early Development, Bioscience In Vivo

AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. AstraZeneca is proud to offer a unique workplace culture that inspires innovation and collaboration. Co-workers are empowered to express diverse perspectives - and are made to feel valued, energised and rewarded for their ideas and creativity

Respiratory & Immunology is one of AstraZeneca's main therapy areas. From a research perspective we work to understand, treat, modify and ultimately cure respiratory and autoimmune diseases with an emphasis on diseases with significant unmet medical need, such as asthma, COPD, Idiopathic Pulmonary Fibrosis (IPF), Chronic Cough and autoimmune diseases (systemic lupus erythematosus (SLE), inflammatory bowel disease (IBD), rheumatoid arthritis (RA)).

To further strengthen our expertise and capacity we are looking for a strong scientist with a great drive for innovation and idea generation as well as excellent laboratory skills to join the Bioscience In vivo Department within the Early Respiratory and Immunology R&D unit located in Gothenburg, Sweden. The team works closely together with other departments to support drug discovery projects and to drive new exciting research. Are you ready to join us?

Key Duties and Responsibilities
As part of the team, you will plan and execute in vivo studies to progress our drug discovery projects and generate publishable scientific insights. You will actively take part in scientific discussions to add valuable input in experimental design and data interpretation.

This is a mainly lab-based role where you will be involved in ongoing projects focusing on pre-clinical experiments, with responsibility to design, perform and analyse in vivo studies as well as presenting and discussing data and scientific rationales.

What you'll do
* As a Scientist you will be a vital member of the in vivo community and will contribute to the development and characterisation of pre-clinical models of autoimmune and/or respiratory diseases to discover novel therapeutics.

* This is a lab-based role where, under the supervision of the team leader and help from colleagues, you will contribute in the planning and execution of experiments, with the responsibility to coordinate, perform and analyse in vivo studies using in vitro methods.

* You will be a strong team player with high degree of flexibility and collaborative skills to support colleagues and help projects reaching the next milestone according to timelines.

Essential for the role
* B.Sc. or M.Sc. degree in relevant subjects or equivalent level of understanding developed through experience in academia or drug discovery settings.
* Valid education required for compliance to work with live animals in Sweden. (LAS, FELASA)
* Several years of hands-on experience with rodents including live animal handling, drug administration through different routes, blood and organ sampling and processing (spleen, lymph nodes, intestine).
* Ability to organise, execute and interpret the results from in vivo studies according to study plans in agreement with the team leader or other colleagues.
* Hands-on knowledge and ability to use in vitro methods (ELISA, western blot and/or qRT-PCR) to analyse ex vivo samples generated from in vivo studies. (3).
* Ability to design panels and run flow cytometry as well as analysing generated data
* Experience of maintaining the highest standards of welfare and ethical compliance and ensuring the integrity of the generated data. Familiar with using Good Statistical Practice in animal research and applying the 3R's (reduction, refinement and replacement) across the full range of studies.
* Excellent English written and oral communication skills, including presentation skills.
* Strong organisation skills and wiliness to incorporate the views of others in your communication and collaboration.

Desirable for the role
* Good written and oral communication skills in Swedish and experience in writing ethical applications for animal work in Sweden.
* Understanding of autoimmune and autoinflammatory diseases with a specific focus on gut immunology.
* Experience with animal models of respiratory diseases (mainly COPD and IPF) and in vivo PK/PD relationships.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.