Scientist - Cell line development

Xbrane Biopharma AB in Solna is an innovative company developing Biosimilar products to make drugs accessible to less privileged populations globally. This is an exciting opportunity to join an innovative and growing team within the development of Biosimilars.

You will be part of the Upstream Process Development (USPD) team responsible for generating mammalian cell lines for Xbrane’s pipeline and implementing new technologies and processes for continuous platform improvement. You will be working in a high-performing and collaborative environment to ensure that project goals and timelines are met and will have a direct impact on shaping Xbrane’s expression and cell line development platforms.

Responsibilities:

• Develop and implement Xbrane’s expression and cell line development (CLD) platform in collaboration with internal and external partners
• Technical oversight of the CLD platform (from vector construction to single clone selection and stability studies) and ensure that CLD work packages are delivered according to project timelines.
• Represent the CLD function on project teams, making decisions for CLD activities and effectively communicating results, progress, and plans.
• Author reports, process descriptions, and other documents
• Prepare and review cell culture-related project IND submissions and ensure compliance with regulatory requirements during development.
• Provide expertise, educate colleagues, and keep up to date in the field of CLD.
• Identify and resolve key technical issues during project development.

Qualification:

• PhD in a relevant Life Science discipline with a minimum of three years of relevant experience or Master’s degree with a minimum of five years of relevant experience.
• Hands-on experience in mammalian suspension cell culture (e.g., CHO, HEK293, NS0 and Sp2/0 cells) in a pharmaceutical or biotechnology setting.
• Strong technical background in vector construction, transfection, stable pool generation, single-cell cloning, cell bank generation and small-scale protein
• Technical expertise with molecular biology techniques and methods including gene design & modification, PCR/qPCR, DNA extraction and sequencing, transfection, chromosome integration, single-cell cloning and screening, gel electrophoresis & blotting and flow cytometry is highly desirable.
• Experience with monoclonal antibody production and biosimilar development is

You are well organized and possess great time-management skills. You are a team player with excellent communication, presentation and writing skills and you need to be fluent in English.

Xbrane is a Great Place to Work certified company that offers an opportunity to grow in your professional role, as well as the opportunity to influence and further develop the company as a whole alongside a highly competent team.

If you have a can-do attitude and on top of that share our values, Make it happen, Beat yesterday, Impossible is nothing and We win as one, you will prosper with us.

Interested?
In this recruitment, Xbrane is collaborating with Mpya Sci & Tech.

Please submit your application no later than the 23th of October. Interviews will be scheduled continuously. Questions? Please contact Johan Östman, +46(0)76 628 78 91 or johan.ostman@mpyascitech.com

About Xbrane Biopharma

Xbrane Biopharma is a Swedish biotechnology company that develops and manufactures biosimilars. Xbrane has a patented protein production platform and world-leading expertise within biosimilar development. This is a Great Place to Work certified company with an entrepreneurial spirit that focuses on being creative and coming up with new ideas as well as on following a rigorous process to bring those ideas to fruition. Xbrane’s headquarter is located at Solna Campus, just outside of Stockholm, for more information see www.xbrane.com.