Scientist NGS/Transcriptomics - Oligonucleotide therapies

At AstraZeneca we win through science, it’s at the heart of our every success. That science is only possible when we all work together – we’ll always make sure you’re clear about how your role is connected to our wider mission to really show what science can do.

Right now, we are looking for a passionate and hard-working Molecular Biologist with NGS skills to join our Drug Molecular Profiling - NGS & Transcriptomics team at AstraZeneca in Gothenburg, Sweden. You will contribute with your expertise in applying molecular biology and NGS expertise to the discovery of novel oligonucleotide therapies.

This role requires significant experience in NGS laboratory practice, additionally the individual will have outstanding team working skills and a proven track record of working collaboratively to ensure scientific excellence and robust delivery to science projects.

Are you motivated by challenging the boundaries of science? Would you like to contribute directly to AZ’s strategy of growth through Innovation? Then please Join us at our R&D site in Gothenburg, Sweden.


Responsibilities
Main Duties and Responsibilities
This role is a scientific specialist in the NGS/Transcriptomics area - a hands-on lab-based role at the forefront of NGS /Transcriptomics technology with a focus on effective delivery, troubleshooting and putting ideas into action. In this role, you will implement NGS methods tools and strategies applied to a wide range of clinical and preclinical projects across a range of diseases, species and drug modalities.

We will rely on you to:
This role is for a Molecular Biologist with significant NGS expertise, which you will apply to the characterization and profiling of the effects of oligonucleotide treatments in in vitro and in vivo cellular assays and models in support of novel drug discovery projects.

Our team is a collaborative group and you will engage in the supervision and mentorship of other scientists, ensuring that methods run expertly and accurately, developing and guiding the set-up of new techniques. Included in the role is also to nurture strong collaborative relationships with the project investigators, key partners, and data scientists to ensure the smooth running of projects.

Your profile
Essential Requirements
• Ph.D. degree or MSc with corresponding experience in a relevant scientific discipline.
• Hands on lab-based experience in utilizing advanced molecular biology RNA-sequencing techniques including Single Cell Transcriptomics or Spatial Transcriptomics.
• This experience will cover all relevant aspects from hypothesis generation, through experimental design and execution, large scale RNA and DNA extraction, sample and library preparation, sequencing, data handling, post sequencing QC and trouble shooting.
• Experience in the detection of nucleic acids in high throughput assays and approaches.
• Excellent organizational and communication skills.

Desired qualifications
• Working with laboratory automation / liquid handling systems, method and technology development and optimization.
• Hands-on laboratory experience running NGS platforms (Illumina, Oxford Nanopore etc).
• Sample Tracking by LIMS systems.

About the organisation
This position is a consultant assignment at AstraZeneca via QRIOS Life Science & Engineering in Göteborg until 2022-12-31. During this time you will be employed by QRIOS Life Science & Engineering.
QRIOS employs curious experts in IT, Life Science and Engineering. We want to continue to attract the best employees, to continue to support our partners with the important competences you require. We are a recruitment and consulting company that is strongly inspired by those who never stop looking for new solutions. As we say, QRIOS MINDS GO FURTHER

Why AstraZeneca?
Our Gothenburg site is one of AstraZeneca's three strategic R&D centers. With more than 2,400 employees from over than 50 countries, our vibrant Gothenburg site is a truly inspiring place to work. Here, the history and future of scientific breakthrough come together. We believe that the diversity of our people is crucial to bringing new discoveries to life.