Scientist/Senior Scientist – Protein Expression Team, AstraZeneca

Job description
At AstraZeneca we use scientific excellence as the foundation to drive success of our drug discovery pipeline. Such excellence stems from strong collaboration, clear direction and a focus on applying cutting-edge research to support drug discovery.

An opportunity is now available for a highly motivated Scientist/Senior Scientist to join the Protein Expression Team within Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D in Gothenburg, Sweden. Leading from the bench, you will apply proven skills in molecular biology, recombinant protein expression, a passion for investigating scientific questions, combined with strong team working ethics, to drug discovery projects. You will join our team whose remit is to support drug discovery projects globally with delivery of impactful recombinant protein reagents used for disease target identification and validation right through to clinical candidate evaluation. This is a consulting position at AstraZeneca in Gothenburg.

As part of a team within the Discovery Sciences organisation, you will be working within a vibrant scientific environment to support drug discovery. We push scientific advances in small molecules, oligonucleotides as well as other emerging technologies, always with a view to providing medicines to improve patient care. The Discovery Biology Department of Discovery Sciences is responsible for the generation of novel reagents and assays to support projects in the drug discovery pipeline from target discovery all the way to clinical candidate.

Responsibilities
This is a lab-based role, generating bespoke protein reagents to support projects in all phases of the discovery process. The role involves application of leading molecular biology techniques to design expression constructs, make DNA constructs for protein expression, producing recombinant proteins that impact projects, as well as troubleshooting. In addition, you will be required to make a significant contribution to the development and application of novel science to advance our capabilities in the production of molecular biology tools used in early drug discovery.

Qualifications
Essential Requirements
Master or Ph. D in Molecular Biology, Biotechnology, Cell Biology, Biochemistry or a related discipline, or 3 years of relevant working experience within Biotechnology
Substantial expertise in cell culture for recombinant protein expression in a variety of eukaryotic cell types, at scales from 1ml to 20L
Excellent communication skills and an ability to operate effectively in a multi-disciplinary research environment
Independent analysis and evaluation of complex data and delivery of data to agreed timelines
Proven ability in providing technical leadership and guidance to others
Maintain an awareness of relevant scientific and technical advances to help identify opportunities for capability development

Desirable Requirements
Experience in design of DNA construct for recombinant protein expression is highly desirable
Experience in use of automation equipment such as liquid handling platforms is desirable
Experience in expression of recombinant expressed proteins in baculovirus-infected insect cells
Good understanding of drug discovery and how to contribute with scientific expertise within own area of expertise to drive project progression
Excellent problem-solving skills, not limited to own area of expertise
Clear and firm decision-making skills, coupled with tenacity to see decisions through, even in situations of ambiguity

For us, it is important that all competence and skills in the labor market are utilized. We welcome all applicants and strive for diversity.

Application
2021-09-16, selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible.

For more information: Kerstin Karlsson, kerstin.karlsson@randstad.se

About the company
Randstad Life Sciences specializes in the field of science and is part of Randstad, the world leader in recruitment and consulting with operations in 38 countries. With this global network, in combination with our strong local foundation, we can offer a wide range of varied and developing assignments and jobs for you who are a specialist in life science. Our mission is to help you reach your true potential with your career in focus!