Senior Bioinformatics Scientist

Are you a goal-driven Bioinformatician with an analytical attitude? Would you like to make use of your computational skills to help us evolve our Next Generation Sequencing (NGS) analytics? If so, we encourage you to join our journey to develop and deliver novel medicines!

At AstraZeneca, we are currently investing in a broad range of multi-omics capabilities (e.g. transcriptomics, epigenomics, proteomics) and want to expand our multi-disciplinary Quantitative Biology team in Gothenburg, Sweden with a Bioinformatics Scientist - where you will play a key role in supporting, driving and developing multi-omics projects.

Our focus is to provide insights into human biology and facilitate discovery of new therapeutics by improving the biological understanding of the target and its engagement. This includes supporting the identification of novel molecular mechanisms of action by providing data analysis solutions to high dimensional multi-omics datasets. We also drive improvement of the company's ability to prioritize target selection and portfolio projects based on probability of technical success. Does this sound like your next challenge?

What you'll do:

* Develop novel NGS data processing and analysis toolkits and pipelines, including development or internalization of algorithms and techniques
* Impact, prototype and build local and global data management processes and solutions for collecting and exploiting NGS transcriptomics and other high-dimensional omics data types
* Design and deliver robust and impactful transcriptomics studies via processing, analysis and interpretation of data.

Essentials in the role:
We believe you are a skilled Bioinformatician with a consistent track record of delivering analytical solutions for business or academic needs. Your ability to convert details into holistic information by collaborating with colleagues, as well as customers will be of great importance.

We expect you to have:

* PhD or similar research experience in Bioinformatics, Mathematical Statistics, Computer Science or another quantitative discipline
* Proven experience in data analysis, management and visualization in several of the following core areas: RNA or DNA based NGS, multivariate and/or high dimensional omics integration, single-cell transcriptomics, epigenomics, metagenomics
* Proficiency and deep understanding of modern NGS methodology: ((sc)RNA-seq, ChIP-seq, (sc)ATAC-seq etc.)
* Experience in either Python (Pandas and NumPy stack) or a lower level programming language (C++, Java, etc.)
* Fluency in R, Bioconductor, RMarkdown and related tools
* Proficiency in working in a Linux environment, experience with shell scripting and standard command line tools
* Basic understanding of molecular biology, cell biology and human physiology

Desirable in the role:

* Familiarity with git, conda and tools such as Snakemake or Nextflow
* Experience in non-NGS transcriptomics technologies

If this sounds like the job and place for you to make a change - apply today!

Welcome with your application no later than 16th August, 2020.

More information
For more information about the position please contact Hiring Manager, Petr Volkov at +46 31 776 14 78 or petr.volkov@astrazeneca.com.

Additional information
Read more about our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Curious about life in Gothenburg? Please visit: https://www.movetogothenburg.com/