Senior Director Physician-Medical Science Dir.

Senior Director Physician - Medical Science Director - Early Clinical Development

The arena
Reporting to the Vice President, Translational Medicine, RIA, the Medical Science Director is a business-critical and influential role with high level accountabilities. The successful candidate will lead the early clinical development of at least 2 compounds in the portfolio. As role holder you will get a unique experience of translational science interacting with clinical medicine.

As role holder you will work in an exciting environment and join a team of 17 including 5 medically qualified MSDs. 3 scientists. We have close links with RIA iMed and provide clinical input and plans for all small molecules in the early development portfolio and work closely with translational science and personalised healthcare

AstraZeneca believes that the future is looking very exciting for the company, mainly due to a number of significant clinical catalysts and the overall potential of their drug development pipeline. Therefore, for the right person, the opportunities for personal growth are immense - the post-holder will be joining AstraZeneca at a time of substantial growth and positive change and will be part of a department and company which is respected for its outstanding people, strong clinical and scientific acumen, innovation, commercial excellence and modern drug development.

Placement for the Medical Science Director role is in Gothenburg, Sweden (preferred) or in Cambrige, UK.

The role
The Medical Science Director will deliver the Medical Scientific strategies of the Clinical Development Plan (CDP) to the project team, and will have accountability for the clinical risk/benefit, scientific and value content and delivery of the Medical Science components of the project to time & quality.

The role includes responsibility for the design, conduct monitoring, data interpretation and reporting of individual clinical trials whilst ensuring projects adhere to Good Clinical Practice and regulatory requirements. The successful candidate will also be an expert in their own disease/drug field.

The role holder will have responsibility and accountability for delivering clinical work which establishes the platform of evidence in human which credentials the target linkage to human disease. Identifying populations where given targets were driving human disease though interventional and non-interventional clinical studies. In addition the post holder will use their clinical/scientific acumen to maximise the efficient delivery of the highest quality clinical data in support of the ongoing strategy.

Typical Accountabilities
Single point accountable leader for the design, delivery and interpretation of clinical studies ensuring the ethical and scientific integrity of the plans, studies and the product in compliance with GCP
Designs or manages the implementation of the medical strategy within Clinical Development globally
Develop clinical evidence for functional relevance of targets in human disease
Support qualification of pharmacodynamic/disease markers for early assessment of efficacy.
Ensure that clinical input into the Translational Medicine and development strategies and plans receive adequate peer consultation to assure high scientific quality
Maintains..............................................................FOR FULL JOB DESCRIPTION AND TO APPLY, please visit www.astrazeneca.se/karriar.