Senior Research Scientist - Analytical LC/MS Characterization

AstraZeneca is one of the world's most exciting biopharmaceutical companies. From scientists to sales, lab techs to legal, we're on a mission to turn science into life-changing medicines that improve patients' lives and benefit society.

AstraZeneca R&D, Physical & Analytical Chemistry, Gothenburg, Sweden now seek to recruit a Senior Research Scientist responsible for Analytical LC/MS Characterization in the Therapeutic Area Respiratory and Immunology (R&I).

AstraZeneca is committed to the development of the next generation innovative respiratory medicines. Respiratory & Immunology is one of AstraZeneca's three therapy areas and is a key growth driver for the Company. Building on our 50-year heritage, we are an established leader in respiratory care across inhaled and biologic medicines.

The Medicinal Chemistry department in the therapeutic area of Respiratory & Immunology is focused on the delivery of Small Molecule (SM) and New Modalities (NM) clinical candidates. Our Physical and Analytical Chemistry team, embedded in Medicinal Chemistry, is crucial for the delivery of clinical compounds, working with a strong research focus in close collaboration with Medicinal and Computational Chemists and other scientists in neighboring functions. We jointly aim at the discovery of the respiratory medicines of the future.



Major Duties and Responsibilities

We are looking for a candidate with a very strong background in Analytical Chemistry and documented expertise in chromatography and mass spectrometry. In this role, the candidate will support drug discovery projects with state-of-the art analytical chemistry, mainly by LC/MS, in a timely manner. As an experienced analytical scientist, the candidate will demonstrate the ability to independently analyze and communicate results, and to engage and collaborate across boundaries with a problem-solving attitude and delivery focus.

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Lab-based research position, independently analyzing and reporting analytical results into project teams. Strong research focus!
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Analysis of novel compounds by U(H)PLC/HRMS methods in an efficient and timely manner, including In-depth characterization of in-vivo compounds by MS/MS
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Supporting Medicinal Chemistry teams with relevant analytical profiling of intermediates and final compounds
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Collaborative mindset, within the analytical team and with colleagues in other disciplines and functions



Essential requirements

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PhD in Analytical Chemistry or equivalent experience
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Theoretical in-depth knowledge and practical expertise in mass spectrometry and method development for U(H)PLC/MS
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Strong scientific curiosity in novel applications and new technology related to analytical chemistry
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Experience from time-of-flight MS and Q-TOF MS instrumentation is a merit
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Demonstrated expertise in structural elucidation by MS/MS is a merit.
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Experience from automation of analytical workflows is a merit
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Track record of successful cross-functional collaborations is a merit



Why AstraZeneca?

At AstraZeneca we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There's no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We're on an exciting journey to pioneer the future of healthcare.



We would like to know more about you. If you are interested, apply now!



We welcome your application no later than 30 April 2021





Where can I find out more?

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