Senior Research Scientist, Bioscience In Vivo

AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. AstraZeneca is proud to offer a unique workplace culture that inspires innovation and collaboration. Co-workers are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity


About the position
Respiratory & Immunology is one of AstraZeneca’s main therapy areas. From a research perspective we work to understand, treat, modify and ultimately cure respiratory and autoimmune diseases with an emphasis on diseases with significant unmet medical need, such as asthma, COPD, Idiopathic Pulmonary Fibrosis (IPF), Chronic Cough and autoimmune diseases (systemic lupus erythematosus (SLE), inflammatory bowel disease (IBD), rheumatoid arthritis (RA)).

To further strengthen our expertise and capacity we are looking for a strong scientist with a great drive for innovation and idea generation as well as excellent laboratory skills to join the Bioscience In vivo Department within the Early Respiratory and Immunology R&D unit located in Gothenburg, Sweden. The team works closely together with other departments focusing on Target Translational Science, Bioscience In vitro assays and Drug Metabolism/Pharmacokinetics to support drug discovery projects and to drive new exciting research. Are you ready to join us?


Responsibilities
As part of the team you will plan and execute in vitro experiments to progress our drug discovery projects and generate publishable scientific insights. You will actively take part in scientific discussions to add valuable input in experimental design and data interpretation.

This is a mainly lab-based role where you will be involved in ongoing projects focusing on pre-clinical experiments, with responsibility to design, perform and analyse in vitro experiments as well as presenting and discussing data and scientific rationales. We are looking for someone with experience in in vitro skills in celluar and molecular biology techniques.

Accountabilities
• You will be an effective and innovative team member in supporting drug discovery projects to meet their objectives
• To conduct where appropriate in parallel more than one area of work to agreed timelines
• You will be responsible for maintaining the highest standards of data integrity
• You will work alongside committed scientists and perform hands-on in vitro work
• You will be responsible for the analysis of mediators in several matrixes from in vivo studies
• You will contribute to the evaluation and interpretation of primary data and write reports, summaries and present in meetings

Your profile
Essential requirements
• PhD in a relevant discipline (area of Bioscience) or MSc complemented with an extensive proven track record of in vitro work
• Experience and ability to independently plan, execute, analyze and interpret results from various cellular and molecular biology techniques, such as for the measurement of protein expression and activation (including FACS analysis, protein isolation from tissues, ELISA, Meso Scale Discovery (MSD) technology platform) and RNA analysis (extraction, qRT-PCR).
• Familiariality with column-based cell isolation techniques (such as MACS, Stem Cell technology)
• Basic understanding of pharmacology, physiology and immunology
• Understanding of statistical methods, quality control and data reporting/archiving
• Problem-solving skills related to in vitro research and data analysis
• Good written and oral communication skills in English
• Positive and goal oriented attitude
• Good social and communication skills and strong team player incorporating the views of others
• Good organisational skills

Desirable requirements
• A proven track record of demonstrating a well-organized customer focused approach, preferably gained within a drug discovery environment.
• Experience on pre-clinical work within autoimmune diseases such as IBD, RA and SLE, and respiratory disease knowledge, including target and mechanistic comprehension of COPD, asthma, cough, IPF, tissue regeneration.

About the organisation
Why AstraZeneca?
It’s our combination of curiosity and courage that drives us, inspired by the possibility of doing things that have never been done before. Empowered to step up, we free ourselves from fear of failure to dig deep into the biology of complex diseases and make bold decisions. Celebrating our successes and failures along the way.

This position is a consultant assignment at AstraZeneca via QRIOS Life Science & Engineering in Göteborg for 4 months. During this time you will be employed by QRIOS Life Science & Engineering.

QRIOS employs curious experts in IT, Life Science and Engineering. We want to continue to attract the best employees, to continue to support our partners with the important competences you require. We are a recruitment and consulting company that is strongly inspired by those who never stop looking for new solutions. As we say, QRIOS MINDS GO FURTHER.