Senior Research Scientist - Bioscience In Vivo, AstraZeneca

Job description
Research Scientist/ Senior Research Scientist, R&I Research and Early Development, Bioscience In Vivo

Reporting to: Team Leader in Bioscience In Vivo department
Placement: Gothenburg, Sweden

AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. AstraZeneca is proud to offer a unique workplace culture that inspires innovation and collaboration. Co-workers are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity

Respiratory & Immunology is one of AstraZeneca’s main therapy areas. From a research perspective we work to understand, treat, modify and ultimately cure respiratory and autoimmune diseases with an emphasis on diseases with significant unmet medical need, such as asthma, COPD, Idiopathic Pulmonary Fibrosis (IPF), Chronic Cough and autoimmune diseases (systemic lupus erythematosus (SLE), inflammatory bowel disease (IBD), rheumatoid arthritis (RA)).

To further strengthen our expertise and capacity we are looking for a strong scientist with a great drive for innovation and idea generation as well as excellent laboratory skills to join the Bioscience In vivo Department within the Early Respiratory and Immunology R&D unit located in Gothenburg, Sweden. The team works closely together with other departments focusing on Target Translational Science, Bioscience In vitro assays and Drug Metabolism/Pharmacokinetics to support drug discovery projects and to drive new exciting research. Are you ready to join us?

Responsibilities
Key Duties and Responsibilities:
As part of the team you will plan and execute in vitro experiments to progress our drug discovery projects and generate publishable scientific insights. You will actively take part in scientific discussions to add valuable input in experimental design and data interpretation.

This is a mainly lab-based role where you will be involved in ongoing projects focusing on pre-clinical experiments, with responsibility to design, perform and analyse in vitro experiments as well as presenting and discussing data and scientific rationales. We are looking for someone with experience in in vitro skills in celluar and molecular biology techniques.

Accountabilities:
You will be an effective and innovative team member in supporting drug discovery projects to meet their objectives
To conduct where appropriate in parallel more than one area of work to agreed timelines
You will be responsible for maintaining the highest standards of data integrity
You will work alongside committed scientists and perform hands-on in vitro work
You will be responsible for the analysis of mediators in several matrixes from in vivo studies
You will contribute to the evaluation and interpretation of primary data and write reports, summaries and present in meetings


Qualifications
Essential requirements:
PhD in a relevant discipline (area of Bioscience) or MSc complemented with an extensive proven track record of in vitro work
Experience and ability to independently plan, execute, analyze and interpret results from various cellular and molecular biology techniques, such as for the measurement of protein expression and activation (including FACS analysis, protein isolation from tissues, ELISA, Meso Scale Discovery (MSD) technology platform) and RNA analysis (extraction, qRT-PCR).
Familiariality with column-based cell isolation techniques (such as MACS, Stem Cell technology)
Basic understanding of pharmacology, physiology and immunology
Understanding of statistical methods, quality control and data reporting/archiving
Problem-solving skills related to in vitro research and data analysis
Good written and oral communication skills in English
Positive and goal oriented attitude
Good social and communication skills and strong team player incorporating the views of others
Good organisational skills

Desirable requirements:
A proven track record of demonstrating a well-organized customer focused approach, preferably gained within a drug discovery environment.
Experience on pre-clinical work within autoimmune diseases such as IBD, RA and SLE, and respiratory disease knowledge, including target and mechanistic comprehension of COPD, asthma, cough, IPF, tissue regeneration.


Application
Deadline: 2022-02-09 , selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible.

For more information:
Please contact Veronika Knudsen veronika.knudsen@randstad.se or Kerstin Karlsson kerstin.karlsson@randstad.se

About the company
Randstad Life Sciences is specialized in competences within Life Science. As a consultant with us, you get a competitive salary, benefits and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many activities.

Randstad Life Sciences specializes in the field of science and is part of Randstad, the world leader in recruitment and consulting with operations in 38 countries. With this global network, in combination with our strong local foundation, we can offer a wide range of varied and developing assignments and jobs for you who are a specialist in life science. Our mission is to help you reach your true potential with your career in focus!