Senior Research Scientist: Cellular assay development

At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with integrity even in difficult situations because we are committed to doing the right thing. We continuously pursue world-class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe.

 

 

As a Senior Research Scientist in cellular assay development in Gothenburg, Sweden, you’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives. You will work within Discovery Sciences, part of AstraZeneca’s BioPharmaceuticals organisation, which focuses on scientific advances in drug discovery across therapeutic areas including, respiratory and inflammation (R&I) and cardiovascular and metabolism (CVRM).
We have an exciting opportunity for you to join us as a lab-based scientist to develop state-of-the-art cell-based screening assays. These assays will be used to support discovery of therapeutic oligos in AstraZeneca’s drug discovery pipeline.
To be successful in the role as Senior Research Scientist we believe you are a highly motivated scientist with a passion to make a difference for patients. We see you as a person who enjoys collaboration and team working, who holds networking skills with experience of interacting effectively across interfaces of functions, disciplines, and cultures. This goes hand in hand with strong delivery focus, problem-solving and communication skills.

 

ESSENTIAL REQUIREMENTS
• PHD IN BIOLOGY, PHARMACOLOGY, CELL BIOLOGY OR A RELATED DISCIPLINE OR A BSC/MSC DEGREE WITH SIGNIFICANT RELEVANT EXPERIENCE, PREFERABLY IN THE PHARMACEUTICAL OR BIOTECHNOLOGY INDUSTRY
• STRONG EXPERIENCE IN CELL BIOLOGY TECHNIQUES APPLIED TO DEVELOPMENT OF PHYSIOLOGICALLY RELEVANT CELLULAR ASSAYS
• A PRACTICAL UNDERSTANDING OF A WIDE RANGE OF CELLULAR ASSAY METHODS AND TECHNOLOGIES INCLUDING QPCR AND IMAGING APPLIED TO COMPOUND PROFILING AND SCREENING
• EXCELLENT COMMUNICATION SKILLS AND AN ABILITY TO OPERATE EFFECTIVELY IN A MULTI-DISCIPLINARY RESEARCH ENVIRONMENT
• ABILITY TO INDEPENDENTLY ANALYSE AND EVALUATE COMPLEX DATA AND DELIVER DATA TO AGREED TIMELINES

DESIRABLE REQUIREMENTS
• Expertise in a range of cell biology techniques, including mammalian cell culture, transfection methods and gene expression knock-down (RNAi or other)
• Expertise in the design, development and validation of cellular assays for compound screening and profiling including ASOs, siRNAs or saRNAs
• Experience with automation of cell assays, e.g. work with liquid handlers like Echo, BRAVO, CyBi well or Dragonfly
• Experience with design of experiments and statistical analysis of assay performance
• Track record of identifying and adopting scientific and technical advances
• Excellent problem-solving skills, not limited to own area of expertise

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.

 

ABOUT ALTEN

Every employee is equally valuable in the success of ALTEN! We are driven by making people grow and develop, which is why we offer you the opportunity to work with what you are truly passionate about. At ALTEN, we have a broad range of assignments at most of the leading companies in Sweden in several different sectors, to make it possible for your wishes to come true. We offer both national and international opportunities and together with your coaching manager, you build your career path so you constantly are able to develop and achieve your goals and dreams! As a consultant at ALTEN, you will get the genuine team feeling at your assignment but also a wonderful togetherness at ALTEN. Through our different internal networks, you will get the opportunity to drive topics and activities that are close to your heart, together with your colleagues. Work life balance is our top priority. We also have a collective agreement and other benefits like Pension, Insurances and Wellness grants.

 

We believe in growing together!