Senior Research Scientist: Cellular assay development,

Job description
Senior Research Scientist: Cellular assay development for oligo drug discovery

At AstraZeneca we work together across global boundaries to find answers to challenges and improve patients’ lives. We continuously pursue world-class medicines in new ways. We do this with integrity because we are committed to doing the right thing.

We have an exciting opportunity for you to join us as a lab-based scientist to develop state-of-the-art cell-based screening assays. These assays will be used to support discovery of therapeutic oligos in AstraZeneca’s drug discovery pipeline.

Responsibilities
As a Senior Research Scientist in the oligo assay development team in Gothenburg, Sweden, you will channel scientific capabilities to make a positive impact in drug discovery projects. You will work within Discovery Sciences, part of AstraZeneca’s BioPharmaceuticals organisation, which focuses on scientific advances across therapeutic areas including respiratory and inflammation (R&I) and cardiovascular and metabolism (CVRM).

To be successful in the role as Senior Research Scientist we believe you are a highly motivated scientist with a passion to make a difference for patients. You have a strong delivery focus as well as problem-solving and communication skills. You enjoy collaboration and team working and have experience of interacting effectively across cultures and disciplines.

Qualifications
Essential Requirements
BSc/MSc degree in Biology, Biotechnology, Cell biology, Pharmacology or related discipline and relevant experience, preferably from the pharmaceutical or biotechnology industry
Hands-on experience with mammalian cell culture and cell biology techniques, preferably with many diverse cell lines
A practical understanding of assay development for high-quality and robust cell-based assays, preferably for compound screening and profiling
Experience with a wide range of cell assay methods and technologies including qPCR, imaging and reporter assays
Excellent team work, problem-solving and communication skills
Ability to independently analyse complex data and deliver data to agreed timelines

Desirable Requirements
PhD in Biology, Biochemistry, Cell biology, Pharmacology or related discipline
Experience in assay development with oligos, e.g. ASOs or siRNAs, preferably in a drug discovery setting
Expertise in a range of cell biology techniques including transfection methods and gene expression knockdown
Experience in high-content imaging and image analysis
Expertise in the design, development and validation of cellular assays. For example, experience in design of experiments and statistical analysis of assay performance
Experience with automation of cell assays, e.g. work with liquid handlers like Echo, BRAVO, CyBi well or Dragonfly


Application
Deadline 2021-11-25,  selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible. We look forward to your application!


For more information: Kerstin Karlsson kerstin.karlsson@randstad.se or Veronika Knudsen veronika.knudsen@randstad.se

About the company
Randstad Life Sciences specializes in the field of science and is part of Randstad, the world leader in recruitment and consulting with operations in 38 countries. With this global network, in combination with our strong local foundation, we can offer a wide range of varied and developing assignments and jobs for you who are a specialist in life science. Our mission is to help you reach your true potential with your career in focus!