Senior Research Scientist - Cellular Assay Development for AstraZeneca

Presentation

For AstraZeneca we are now looking for a Senior Research Scientist - Cellular Assay Development with focus on Imaging-based Assays for a consultant assignment starting in February and that will go on until 31st of August 2017 with possibility for extension.

AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. AstraZeneca is proud to offer a unique workplace culture that inspires innovation and collaboration. Co-workers are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity
The arena
Discovery Science is a global function within Innovative Medicines, IM, in AstraZeneca. Discovery Science supports innovative medicine project teams from multifunctional capability centers in Alderley Park, Boston and Mölndal. Discovery Sciences is mainly involved in early lead generation through the late Lead Optimization stage of drug discovery. It is composed of several capabilities where Reagent and Assay Development (RAD) is one among several others such as Screening Sciences and Structure & Biophysics. This position will be placed in the RAD Department where we focus on delivering different types of reagents and assays for high impact into the drug development.

Interviews and selections are held on an ongoing basis so please apply today!

Arbetsuppgifter

The role
To provide strong expertise in the competency of Cellular Assay Development and with a strong focus on imaging-based cellular assays. To devise, champion and develop scientific areas, aligned with project needs. To be lab-focused and make significant contributions to the practical delivery of project goals through proposal and execution of experimental strategies and troubleshooting of problems.

It is essential to have good social and communication skills and to be a strong team player. Candidates should be able to work independently, take own initiatives and have a positive, goal oriented and problem solving attitude. Good organisational skills are required and you should be comfortable in presenting your results. Excellent English is required, both spoken and in writing.
Tasks
- To develop imaging-based cellular assays for target identification, target validation and phenotypic assay development
- To use qualitative and quantitative image-based cellular assays and analysis methods for drug screening, cell profiling/QC and protein expression/functionality in a biologically and statistically relevant manner

Utbildning/erfarenhet

The following skills are highly desirable
- Ability to develop imaging assays for predefined endpoints and/or investigate assay space to determine optimum endpoint for projects
- In depth knowledge of one or more imaging platforms (CellInsight, Image Express, CV7000) which can be used to generate multiparameter cellular data
- Experience using Columbus image analysis software
- Culturing and functional characterization of recombinant cell lines, primary cells and iPSC
- Expertise in cell-based assay design including knowledge of detection technologies, including spectroscopic (e.g. absorbance, fluorescence modalities), luminescent, label-free detection and imaging
- Practical understanding of assay development and optimisation, including statistical tools such as factorial experimental design, to enable generation of robust, reproducible and sensitive assays

Accountabilities
- To use judgment and knowledge where appropriate to influence the work of the project, team, section and department
- To work independently to contribute to the design and analysis of experimental procedures by incorporating the views of others
- To interpret experimental data and play a significant role in the planning of further experiments
- To identify and solve problems associated with their experiments
- To schedule agreed work-plans over agreed timelines such that the objectives of the team are met

Minimum experience
You should have a Ph. D. degree or corresponding experience in a relevant scientific discipline with extensive experience in drug discovery.

Förmåner

We take good care of our consultants and we offer social activities, as well as help in planning your future career. Your consultant manager is well experienced from your field, and knows how to get the most out of your assignment.

As a Poolia employee, you are included in the requirements concerning agreements on terms of employment by Unionen. Moreover, you get a grant for working out at your choice of place. You are also covered by a health insurance.

Företagsbeskrivning

Poolia Life Science can offer several opportunities for skilled people with a background in biochemistry, chemical engineering or science. We work with Sweden’s leading pharmaceutical and life science companies. So whether you’re interested in research, regulatory affairs, quality assurance, environmental and quality control, sales and marketing, or just want a career change, we have the job for you.

Working as a consultant suits whoever wants to get a lot of experience in a short period of time. We offer you the chance to work with well-known brands at renowned companies where you can develop your skills. If you’re looking for a world of exciting assignments and new contacts, you’ll like being a consultant.

AstraZeneca is a major international healthcare company engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. But we are more than one of the world’s leading pharmaceutical companies - at AstraZeneca, we are proud to have a unique culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.

Sluttext

Please apply by registering your CV here on our website. Click on the "Ansök" button to the right. It is our recommendation that you register as much information as possible and that you attach a complete CV-document. Please check that your correct e-mail address is registered.

Poolia is a registered staffing agency, meaning that we comply with the requirements set by Bemanningsföretagen - the Swedish Association of Staffing Agencies.

Language

en-GB