Senior Research Scientist Cellular Assay Development Gothenburg

Job description
At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with the upmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe.

As a Senior Research Scientist in cellular assay development in Gothenburg, Sweden, you’ll play a pivotal role in channelling our scientific capabilities to make a positive impact on changing patients’ lives. You will work within Discovery Sciences, part of AstraZeneca’s BioPharmaceuticals organisation, which focuses on scientific advances in established and emerging medicine formats and drug discovery technologies across therapeutic areas including, respiratory and inflammation (RIA), cardiovascular and metabolism (CVRM).

We have an exciting opportunity for you to join Discovery Sciences’ Discovery Biology Department as a lab-based scientist in the Cellular Assays Team developing state-of-the-art cell-based screening assays and detailed biological mechanism-of-action studies to support projects in all phases of AstraZeneca’s drug discovery pipeline with a significant focus in RIA and CVRM disease areas.

Specifically, the successful candidate will take a lead scientific role in applying their skills using imaging technologies and developing high content assays.

Responsibilities
 Lab-based scientist utilizing expertise in cellular assay development; independently designing, developing and validating assays for implementation in drug discovery projects, while incorporating the views of others
 Work in partnership with colleagues in the High Throughput Screening and Mechanistic Biology & Profiling teams and across the organisation 
 Design and implement work-plans to agreed timelines to meet project objectives, including delivery of more than one agreed area of work in parallel
 Be an effective member of Drug Discovery Project Teams, contributing novel ideas and using judgement and knowledge to influence the work of the project
 May lead one or more aspects of scientific discipline within the team
 Maintain an awareness of current developments in the literature and contribute to the continuous capability enhancement process by identifying opportunities where improvements can be made
 Achieve personal scientific visibility through project contributions and internal presentations at departmental or functional meetings; and external scientific visibility through poster and oral conference presentations and authorship on peer-reviewed publications


Qualifications
Essential Requirements
 PhD in Biology, Pharmacology, Cell biology or a related discipline or a BSc/MSc degree with significant relevant experience, preferably in the pharmaceutical or biotechnology industry
 Strong experience in cellular biology techniques applied to development of physiologically relevant cellular assays 
 Expertise in the design, development and validation of cellular imaging assays for compound profiling
 Experience in advanced and automated fluorescent based imaging platforms
 Experience in use and development of scripts for quantitative image analysis  


Desirable Requirements
 A practical understanding of a wide range of cellular assay methods and technologies (e.g., fluorescence, luminescence, target engagement techniques, plate-based automation) as applied to a range of biological targets for compound profiling and screening
 Good publication records in peer-reviewed journals preferably in the field of RNA degradation biology
 Excellent problem-solving skills, strong delivery focus and communication skills
 Research experience in RIA and/or CVRM diseases
 Excellent team working and networking skills with experience of interacting effectively across interfaces of discipline, culture, and expertise

For us, it is important that all competence and skills in the labor market are utilized. We welcome all applicants and strive for diversity.

Application
2020-03-05, selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible.
For more information: Kerstin Karlsson kerstin.karlsson@randstad.se or Eleonor Ehrman +46733434109. 

About the company
Randstad Life Sciences specializes in the field of science and is part of Randstad, the world leader in recruitment and consulting with operations in 38 countries. With this global network, in combination with our strong local foundation, we can offer a wide range of varied and developing assignments and jobs for you who are a specialist in life science. Our mission is to help you reach your true potential with your career in focus!