senior research scientist genome editing astrazeneca gothenburg

Job description
AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. AstraZeneca is proud to offer a unique workplace culture that inspires innovation and collaboration. Co-workers are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.

The Arena
The precise genome editing group is developing new tools and technologies to facilitate target validation, speedy disease modeling and to evaluate the potential applications and safety of therapeutic genome editing. We are part of the Translational Genomics department where we develop advanced cellular and animal models and we also provide expert support for Next Generation Sequencing and Transcriptome analysis. The candidate will be embedded in an international group working on cutting edge technologies with world leading external collaborators.

This is a temporary consultant position, lasting for 12 months. 

Responsibilities
To design and build genome editing-based strategies and tools required to generate in vivo (mouse) and in vitro reagents to create disease models
To develop delivery tools to improve the efficiency of genome editing
To perform confirmation of genetic manipulation and functional validation of engineered cells and animals
To perform target validation studies in early projects


Qualifications
Minimum requirements
Molecular biology expertise on vector design and genetic manipulation of cell lines and/or mouse embryonic stem cells, primary and iPSC cells
Functional characterization of gene modified cell lines (DNA, RNA and protein levels, cellular assays)
In silico construct design and analysis of genetic perturbation after genome editing


Preferred experience and key factors
Previous practical expertise with genome editing tools including Cas9/CRISPR, ZFNs and TALENs
Hands on experience with RNA and protein detection, Next Generation Sequencing library preparation and results analysis


For us, it is important that all competence and skills in the labor market are utilized. We welcome all applicants and strive for diversity.

Application
2020-02-26, selection and interviews will be ongoing. The position may be filled before the last day.
For more information:  Galia Nyström, consultant manager,  galia.nystrom@randstad.se or Kerstin Karlsson, consultant manager, +4673-0848695.

About the company
Randstad Life Sciences is specialized in competences within Life Science. As a consultant with us, you get a competitive salary, benefits and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many social activities.

Randstad Life Sciences is part of Randstad, the world leader in recruitment and consulting with operations in 38 countries. With this global network, in combination with our strong local foundation, we can offer a wide range of varied and developing assignments and jobs for you who are a specialist in life science. Our mission is to help you reach your true potential with your career in focus!