Senior Research Scientist - human induced-pluripotent stem cell biology

Senior Research Scientist – human induced-pluripotent stem cell biology

Are you an experienced scientist in the field of pluripotent stem cells (PSC)? Would you like to use your scientific skills to drive the development of stem-cell derived models for therapeutic development? If these goals resonate with you, we may be your Team!

At AstraZeneca in Gothenburg, Sweden we have an exciting opportunity for you to join us in the Applied Stem Cell Sciences Team in Discovery Sciences, Biopharmaceuticals R&D, as a 9-months contract bench-based Senior Research Scientist (from March 1st 2023 to November 30th 2023) and impact the development of stem cell models.

About the position
You will be based in Gothenburg Sweden, working alongside with our stem cell scientists, disease area specialists and the genome editing group. Using your strong knowledge and experience in stem cell biology and cell model development you will have the opportunity to work on development of in vitro models and assays that will be applied to study various targets of relevance to disease. You will maintain and differentiate induced pluripotent stem cells (iPSCs) and carry out gene editing experiments where necessary.

Responsibilities
The role is focused on laboratory-based activities. Your biggest impact will be through significant contributions to the practical delivery to projects in compliance with AstraZeneca corporate responsibility, policies and relevant safety standards.
It is essential to have good social and communication skills, be collaborative and a dedicated team player. Candidates should be able to work independently, take their own initiatives and have a positive, goal oriented and problem-solving attitude.
Good organizational, data management and documentation skills are required, and you should be comfortable in presenting your results. English language is required, both spoken and in writing.

Your profile
• BSc/MSc/PhD degree with extensive experience in Developmental and Cell Biology
• Proven experience with human PSC biology and differentiation to kidney and lung cell types
• Experience in developing molecular biology, biochemical and cell-based assays (including qPCR, ELISA, Western blotting, Flow cytometry, immunofluorescence) in iPSC-derived cultures.
• Perform in vitro studies to investigate the effects of CRISPR-based gene editing on gene and protein expression and cellular readouts.
• Effectively collaborate within a matrixed research team to facilitate the success of projects.
• Maintain complete experimental records.

The following skills are highly desirable:
• Experience with CRISPR gene editing, clonal cell line generation
• Expertise with liquid handling automation technologies
• Experience of setting up cell based pharmacological assays

About the organisation
This position is a consultant assignment for 9 months at AstraZeneca in Göteborg. During this time you will be employed by QRIOS Life Science & Engineering.

QRIOS employs curious experts in IT, Life Science and Engineering. We want to continue to attract the best employees, to continue to support our partners with the important competences you require. We are a recruitment and consulting company that is strongly inspired by those who never stop looking for new solutions. As we say, QRIOS MINDS GO FURTHER.