Senior Research Scientist - in vivo model generation

Are you an enthusiastic scientist with a passion for and experience in molecular and cell biology? Do you also possess practised knowledge of DNA cloning of a wide range techniques? Perfect, welcome to combine your scientific drive with your great skills at AstraZeneca!

The Translational Genomics department at AstraZeneca in Gothenburg, Sweden, is growing and we have three exciting opportunities for you as a Senior Research Scientist to join our excellent Preclinical In Vivo Models team. The positions are open for you as a highly passionate and motivated molecular and cell biologist with extensive experience and innovative knowledge in the design and generation of DNA based constructs using a wide range of cloning techniques and their application in science & technology.

Join the team that follows the science unlike anywhere else. This is the place for curious minds. Dig deep into the biology of complex disease and uncover breakthroughs.

What you'll do:
You'll work as one of our specialists in the area of molecular and cell biology, experienced in a variety of cloning techniques used for the generation of complex DNA constructs and their application in the development of advanced transgenic models. You will devise, champion and develop scientific areas aligned with project needs and be an authority in the area of molecular and cell biology and detailed genome editing using both established and the latest techniques to lead projects from a lab-based perspective and to make significant contributions to the practical delivery of AstraZeneca project goals to arrange of therapeutic areas.

Included in the role is also to provide disciplinary scientific expertise and you will propose experimental strategies, troubleshoot problems and make significant contributions to the delivery of projects in compliance with AstraZeneca corporate responsibility policies and relevant safety standards.

Essential for the role:
This role requires proven expertise on molecular and cell biology together with your scientific drive. You should have a Ph.D. degree or corresponding experience in a relevant scientific field or, alternatively, a first degree and significant relevant experience. As well as;

* Molecular biology expertise and experience of working with cell culture.
* Extensive DNA cloning experience and experience of working with Bacterial Homologous Recombination, Gibson assembly and Gateway cloning.
* Practiced skills in confirmation assays of genetic manipulation.
* Working knowledge of the latest precise genome engineering tools such as CRISPR.
* An innovative approach to contribute to the implementation of groundbreaking in vivo models.
* Experience in the generation of scientific presentations and manuscripts for publication.

To be successful as a Senior Research Scientist you also need to enjoy collaboration and team work - and have the skill to interact and communicate efficiently across interfaces of global functions and fields. This goes hand in hand with your problem-solving skills and strong delivery focus.

Desirable for the role:

* Experience of working with preclinical transgenic mouse models.
* Experience in drug discovery.

Why AstraZeneca?
Thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment. With more than 2,400 employees from over 50 countries, our vibrant Gothenburg site is a truly inspiring place to work. Here, the history and future of scientific breakthrough come together. We believe that the diversity of our people is crucial to bringing new discoveries to life.

So what's next? If you meet the above criteria and is looking for an exciting career in Drug Discovery along with great employee benefits as for example competitive salary, extra paid Holiday and availability to our outstanding Fitness Centre - please apply today!

We look forward to your application as soon as possible, but no later than 5th December, 2021.

More information:
For more information about the position please contact hiring manager John Wiseman at john.w.wiseman@astrazeneca.com.

Additional information:
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html