Senior Research Scientist - Mechanistic Biology & Profiling

Do you have a background in biochemistry or cell biology, aren't afraid of trying new paths and doing things differently? Do you also feel passionate about the possibilities of science to change lives? Perfect, your next challenge might be this role at AstraZeneca!

We are seeking a highly motivated, hardworking and scientifically curious scientist to join our Mechanistic Biology & Profiling team as a Senior Research Scientist. You will have the opportunity to utilize your scientific capabilities to contribute to the progression of key drug discovery programs in a highly collaborative environment. The position will be located at our vibrant R&D site in Gothenburg, Sweden.

At AstraZeneca, we're not afraid to do things differently. We're building a new kind of organization to reset expectations of what a biopharmaceutical company can be. This means we are opening new ways of working and pioneering ground-breaking methods. You'll have the opportunity to make a difference in people's lives every single day and our mission is centered on delivering life-changing products that advance world health and help fight and cure disease. If you're inspired by the possibilities of science to make a difference and are ready to discover what you can do - join us.

Mechanistic Biology & Profiling (MBP) is a global department responsible for compound profiling and mechanism of action studies in support of the BioPharmaceuticals Therapy Areas - Cardiovascular, Renal & Metabolism (CVRM) and Respiratory & Immunology (R&I) - and Oncology. MBP is a part of Discovery Sciences - a multidisciplinary department which drives early drug discovery across AstraZeneca's global Research and Development portfolio.

What you'll do:
This is a lab-based role focused on generating in vitro pharmacology data in support of drug discovery projects globally with focus on SAR profiling and detailed mechanism of action data. We offer a highly rewarding scientific environment with ample learning opportunities and an expectation to publish new findings.

You will be an experienced lab-based scientist, able to interact across a broad range of therapeutic projects and global initiatives within Discovery Sciences and externally. You will also represent the group on Project Teams and drive scientific and technical innovation in our strategic area, including the identification and development of innovative processes and workflows to deliver high quality and detailed data efficiently.

Essential in the role:

* Ph.D. in Pharmacology, Biochemistry or a related discipline or a BSc/MSc degree with significant proven experience, preferably in the Pharmaceutical or Biotechnology industry
* Extensive experience in molecular and cellular biology techniques applied to physiologically relevant cellular assays, including cells grown in 3D and organoid settings
* Documented experience in the application of imaging to 3D cultures and organoids
* Scientific visibility and leadership through project contributions and external publications
* Excellent communication skills and an ability to operate effectively in a multi-disciplinary research environment
* Independent analysis and evaluation of complex data and delivery of data to agreed timelines
* First-rate decision-making skills, coupled with tenacity to see decisions through, even in situations of ambiguity

Desirable in the role:

* A proven publication track-record from several labs, such as a postdoctoral experience, in a relevant area is considered meriting
* Compound profiling in patient-near cells, including assessment of variability between donors
* Expertise in the design, development and validation of cellular assays for compound profiling
* Proven ability in providing technical leadership and guidance to others
* Track record of identifying and adopting scientific and technical advances
* Excellent problem-solving skills, not limited to own area of expertise

If this sounds like the position and place for you - apply today!

Welcome with your application, no later than the 24th July 2020.

For more information about the position please contact Thomas Lundbäck at +46 727116689 or thomas.lundback@astrazeneca.com